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孕期用药的长期变化。

Long-term changes in medication during pregnancy.

作者信息

Harjulehto T, Aro T, Saxén L

机构信息

Department of Pathology, University of Helsinki, Finland.

出版信息

Teratology. 1988 Feb;37(2):145-8. doi: 10.1002/tera.1420370207.

Abstract

The Finnish Register of Congenital Malformations, established in 1963, rendered possible the study of changes in medication during pregnancy. The study consisted of 659 control mothers who had delivered a healthy child during the years 1964-1984. The data of this long-term follow-up study were collected by interviews at Maternal Health Care Centers after delivery and were completed by filed antenatal data. The results show a continuous decreasing trend in the usage of analgesics and tranquilizers but not in the usage of antiemetics, antibiotics, and vitamins. We believe that in Finland the publicity aimed at unnecessary medication during pregnancy has affected both the mothers and the health personnel.

摘要

芬兰先天性畸形登记册于1963年设立,使得对孕期用药变化的研究成为可能。该研究包括659名对照母亲,她们在1964年至1984年期间生下了健康的孩子。这项长期随访研究的数据是在产后通过产妇保健中心的访谈收集的,并由存档的产前数据补充完整。结果显示,镇痛药和镇静剂的使用呈持续下降趋势,但止吐药、抗生素和维生素的使用情况并非如此。我们认为,在芬兰,针对孕期不必要用药的宣传对母亲和医护人员都产生了影响。

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