British Columbia Centre on Substance Use, Vancouver, Canada.
Faculty of Health Sciences, Simon Fraser University, Burnaby, Canada.
Drug Alcohol Rev. 2021 Sep;40(6):959-963. doi: 10.1111/dar.13246. Epub 2021 Feb 4.
Illicit drug use while admitted to hospital is common amongst people who use drugs. Furthermore, non-medical prescription opioid use (NMPOU) is increasingly being used by this population. This study was undertaken to investigate the relationship between NMPOU and having ever reported using illicit drugs in the hospital.
This study was a cross-sectional study design based on data derived from participants enrolled in three Canadian prospective cohort studies between December 2011 and November 2016. Using bivariable and multivariable logistic regression analyses, we examined the relationship between NMPOU and having ever reported illicit drug use in the hospital.
Among the 1865 participants (951 male, 471 female) enrolled in the studies, 1422 (76.25%) met the inclusion criteria of having ever been hospitalised. Of these, 436 (30.7%) had used illicit drugs while in the hospital. In multivariable analyses, after adjusting for various confounders, we found a positive relationship between the percentage of reporting at least daily NMPOU in the past 6 months during the cohort study period and illicit drug use in the hospital (adjusted odds ratio 3.42; 95% confidence interval 1.46-8.02).
Among our sample, more persistent NMPOU was positively associated with having reported in-hospital illicit drug use. Our findings point to the need for better identification and management of opioid use disorder in acute care settings to reduce in-hospital illicit drug use, and to offer evidence-based medical treatments to achieve the most optimal outcomes for patients.
在住院期间使用非法药物在吸毒人群中很常见。此外，非医疗处方类阿片类药物的使用（NMPOU）在该人群中也越来越普遍。本研究旨在调查 NMPOU 与在医院报告使用过非法药物之间的关系。
这是一项基于 2011 年 12 月至 2016 年 11 月期间参加三项加拿大前瞻性队列研究的参与者数据的横断面研究设计。使用单变量和多变量逻辑回归分析，我们检查了 NMPOU 与在医院报告过使用非法药物之间的关系。
在纳入的 1865 名参与者（951 名男性，471 名女性）中，有 1422 名（76.25%）符合既往住院的纳入标准。在这些人中，有 436 人（30.7%）在住院期间使用过非法药物。在多变量分析中，在校正了各种混杂因素后，我们发现，在队列研究期间，过去 6 个月中至少每天报告 NMPOU 的比例与医院内非法药物使用之间存在正相关关系（调整后的优势比 3.42；95%置信区间 1.46-8.02）。
在我们的样本中，更持续的 NMPOU 与报告在医院内使用非法药物呈正相关。我们的研究结果表明，需要在急性护理环境中更好地识别和管理阿片类药物使用障碍，以减少医院内非法药物使用，并提供循证医学治疗方法，以实现患者的最佳治疗效果。
