新生儿死后磁共振成像的临床应用。

Clinical Application of Postmortem Magnetic Resonance Imaging in Neonates.

机构信息

Faculty of Health Sciences, Ben Gurion University of the Negev, Beer-Sheva, Israel,

Neonatal Department, Soroka Medical Center, Beer-Sheva, Israel,

出版信息

Neonatology. 2021;118(1):54-63. doi: 10.1159/000512923. Epub 2021 Feb 5.

DOI:10.1159/000512923

PMID:33550296

Abstract

BACKGROUND

Recent reports advocate the use of MRI either as a substitute for postmortem examinations or for a more targeted autopsy.

METHODS

A full-body postmortem MRI (pMRI) of infants was performed as early as possible after death, and findings were compared to clinical premortem diagnoses.

RESULTS

Thirty-one infants were scanned during the study period. Median gestation at birth was 34 weeks (ranges: 24-43). In 3 (10%) cases, no new findings were detected. In 2 (6%), new minor findings not related to the cause of death were detected, and in 17 (55%), new minor findings related to the cause of death were detected. New major findings related to the cause of death were detected in 4 (13%) cases, and new major findings not related to the cause of death were detected in 5 (16%) cases. In 3 (10%), findings thought to alter the perceived cause of death were detected. Overall, in 23 (74%) cases, pMRI findings reinforced the clinical premortem diagnoses.

CONCLUSIONS

pMRI is a culturally accepted alternative when autopsy is not performed and can either reinforce, refute, or add to premortem clinical diagnoses.

摘要

背景

最近有报告提倡将 MRI 用作替代尸检，或者进行更有针对性的解剖。

方法

在死亡后尽早对婴儿进行全身法医磁共振成像（pMRI）检查，并将检查结果与临床生前诊断进行比较。

结果

在研究期间对 31 名婴儿进行了扫描。出生时的中位胎龄为 34 周（范围：24-43）。3 例（10%）未发现新的发现。2 例（6%）发现与死亡原因无关的新的较小的发现，17 例（55%）发现与死亡原因相关的新的较小的发现。4 例（13%）发现与死亡原因相关的新的主要发现，5 例（16%）发现与死亡原因无关的新的主要发现。在 3 例（10%）中，发现了被认为改变了对死亡原因的认识的发现。总体而言，23 例（74%）pMRI 检查结果证实了临床生前诊断。