Sejunaite Karolina, Lanza Claudia, Gaucher Frederic, Klug Roland, Riepe Matthias W
Division of Geriatrics and Old Age Psychiatry, Psychiatry II Ulm University, Ulm, Germany.
Front Psychiatry. 2021 Jan 20;11:611176. doi: 10.3389/fpsyt.2020.611176. eCollection 2020.
Memory for complex content is severely impaired in patients with schizophrenia spectrum disorders, which might make processing of daily information such as news and commercials particularly challenging. The goal of the present study was to assess the impairment of everyday memory in patients with schizophrenia. Healthy controls (HC) and patients with schizophrenia (SZ) were asked to watch a selection of six news segments and six commercials and complete a recognition task on the content of these video clips. All participants completed a neuropsychological test battery comprising measures of attention, working and episodic memory, and executive function. The total number of correctly recognized items was significantly lower in the SZ group. In contrast, the number of false recognitions was alike in both news and commercials paradigm. We conclude that memory in patients with schizophrenia is more prone to omissions than distortions for complex everyday stimuli. The results offer further support for impaired binding in SZ patients. Memory in SZ suffices to reject false multi-feature items on grounds of identifying at least one feature as incorrect but does not suffice to recall all features of a complex item and affirm it as correct.
精神分裂症谱系障碍患者对复杂内容的记忆严重受损,这可能使他们处理新闻和广告等日常信息变得特别困难。本研究的目的是评估精神分裂症患者日常记忆的损害情况。我们让健康对照组(HC)和精神分裂症患者(SZ)观看六个新闻片段和六个广告,并对这些视频片段的内容完成一项识别任务。所有参与者都完成了一套神经心理学测试,包括注意力、工作记忆和情景记忆以及执行功能的测量。SZ组正确识别项目的总数显著更低。相比之下,在新闻和广告范式中,错误识别的数量在两组中相似。我们得出结论,对于复杂的日常刺激,精神分裂症患者的记忆更容易出现遗漏而非扭曲。这些结果为SZ患者的绑定受损提供了进一步支持。SZ患者的记忆足以基于识别出至少一个特征不正确而拒绝错误的多特征项目,但不足以回忆起复杂项目的所有特征并确认其正确。