Arias-Murillo Yazmin R, Benavides-V Carlos A, Salinas-N María A, Osorio-Arango Karime, Plazas-Sierra Carolina, Cortés Jorge A
Coordination of the National Donation and Transplant Network, Blood Bank, Transfusion, and Transplant Research Group, Direction of Public Health Networks, Instituto Nacional de Salud, Bogotá, Colombia.
Fundación Cardioinfantil, Transplant Surgeon, Bogotá, Colombia.
Transplant Proc. 2021 May;53(4):1237-1244. doi: 10.1016/j.transproceed.2020.12.003. Epub 2021 Jan 13.
To assess our determination to continue transplant activity in Colombia during the coronavirus disease 2019 (COVID-19) pandemic, this study seeks to describe the risk of infection and mortality of transplanted patients vs those on the waiting list. Therefore, a descriptive study of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2)/COVID-19 infection in transplant recipients and patients on the waiting list was conducted. The data sources were the information systems of the Instituto Nacional de Salud of Colombia: National Donation and Transplant Information System, the National Public Health Surveillance System, and the National COVID-19 Data Repository. Characteristics of the patients who tested positive were analyzed, and the mortality rate was determined. An Real Time-PCR test for SARS-CoV-2/COVID-19 was performed in 7% of the transplant recipients included in this study, and 14.8% of those recipients tested positive. Among patients on the waiting list, 15.2% were tested, and 16.7% showed positive results. Overall, 1% (84/8108) of the transplant recipients and 2.5% (74/2926) of patients on the waiting list were infected with SARS-CoV-2/COVID-19. There were no differences in mortality between these groups (P = .8748). In conclusion, with the data obtained so far, the hospital availability, and the adoption of safety protocols in the institutions, our findings can support the continuity of the transplant activities in this country.
为评估我们在2019年冠状病毒病（COVID-19）大流行期间继续在哥伦比亚开展移植活动的决心，本研究旨在描述移植患者与等待名单上患者的感染风险和死亡率。因此，我们对移植受者和等待名单上的患者进行了关于严重急性呼吸综合征冠状病毒2型（SARS-CoV-2）/COVID-19感染的描述性研究。数据来源是哥伦比亚国家卫生研究所的信息系统：国家捐赠和移植信息系统、国家公共卫生监测系统以及国家COVID-19数据存储库。分析了检测呈阳性患者的特征，并确定了死亡率。本研究中7%的移植受者进行了SARS-CoV-2/COVID-19的实时聚合酶链反应检测，其中14.8%的受者检测呈阳性。在等待名单上的患者中，15.2%进行了检测，16.7%结果呈阳性。总体而言，移植受者中有1%（84/8108）、等待名单上的患者中有2.5%（74/2926）感染了SARS-CoV-2/COVID-19。这些组之间的死亡率没有差异（P = 0.8748）。总之，根据目前获得的数据、医院的可用资源以及各机构采用的安全协议，我们的研究结果能够支持该国移植活动的持续开展。
