Division of Cardiovascular Surgery, Department of Surgery, Shiga University of Medical Science, Otsu, Shiga, Japan.
Interact Cardiovasc Thorac Surg. 2021 May 27;32(6):864-872. doi: 10.1093/icvts/ivab022.
The aim of this study was to investigate the impact of in situ internal thoracic artery (ITA) grafting ipsilateral to the arteriovenous fistula (AVF) on postoperative outcomes in haemodialysis patients undergoing isolated coronary artery bypass grafting (CABG).
We reviewed 132 haemodialysis patients who underwent isolated CABG between January 2002 and December 2019. With a difference between the left and right upper arms blood pressure measurement of ≥20 mmHg, we did not use the ITA on the lower value side. We categorized patients into 55 patients (41.7%, ipsilateral group) whose left anterior descending artery was revascularized using the in situ ITA ipsilateral to the AVF, and 77 patients (58.3%, contralateral group) whose left anterior descending artery was revascularized using the ITA opposite the AVF. We compared patients' postoperative outcomes after adjusting for their backgrounds using weighted logistic regression analysis and inverse probability of treatment weighting.
No patients developed coronary steal postoperatively, and there was no significant difference in 30-day mortality between the groups (P = 0.353). The adjusted 5-year estimated rates of freedom from all-cause and cardiac death in the ipsilateral vs contralateral groups were 52.3% vs 54.0% and 78.2% vs 88.6%, respectively; survival curves were not statistically significantly different (P = 0.762 and P = 0.229, respectively).
In situ ITA grafting ipsilateral to the AVF was not associated with postoperative early and mid-term worse outcomes in haemodialysis patients undergoing isolated CABG.
本研究旨在探讨同侧动静脉瘘(AVF)与原位内乳动脉(ITA)移植对行单纯冠状动脉旁路移植术(CABG)的血液透析患者术后结局的影响。
我们回顾了 2002 年 1 月至 2019 年 12 月期间接受单纯 CABG 的 132 名血液透析患者。在左、右上臂血压测量值差值≥20mmHg 的情况下,我们不在血压较低侧使用 ITA。我们将患者分为 55 名(41.7%,同侧组),其前降支采用同侧 AVF 内原位ITA 进行血运重建,77 名(58.3%,对侧组),其前降支采用对侧 AVF 内ITA 进行血运重建。我们使用加权逻辑回归分析和逆概率治疗加权对患者的术后结局进行了调整。
没有患者发生术后冠状动脉窃血,两组 30 天死亡率无显著差异(P=0.353)。同侧与对侧组的 5 年全因死亡率和心脏死亡率分别为 52.3%与 54.0%(P=0.762)和 78.2%与 88.6%(P=0.229);生存曲线无统计学差异。
在接受单纯 CABG 的血液透析患者中,同侧 AVF 与原位 ITA 移植并不与术后早期和中期较差的结局相关。