Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. Harrison St. Suite #300, Chicago, IL, 60612, USA.
Department of Psychiatry, Road Home Program, Rush University Medical Center, 325 S. Paulina St. Suite 200, Chicago, IL, 60612, USA.
Eur Spine J. 2021 May;30(5):1365-1379. doi: 10.1007/s00586-021-06747-x. Epub 2021 Feb 10.
As more patients undergo lumbar spine surgery, novel interventions may improve physical and mental health outcomes. Few studies summarize the benefit of cognitive behavioral therapy (CBT) among lumbar spine surgery patients. This study collects randomized control trial data to investigate the influence of CBT on patient reported outcomes among lumbar spine surgery patients.
Our study used the Preferred Reporting Items for Systematic Reviews and Meta-Analyses and a medical library expert assisted in searching PubMed/MEDLINE, Scopus, CINAHL, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, PsycINFO, and Google Scholar. We calculated standardized mean differences (SMD) to evaluate the effect size of CBT versus control groups with a sensitivity analysis.
Our meta-analysis included seven studies with a total of 531 patients. The majority of included studies evaluated lumbar fusion, with preoperative CBT performed by physiotherapists. The largest effects were observed for overall quality of life (SMD = 0.55 [95% CI 0.05, 1.05], p < 0.001, I = 86.7%) and psychological outcomes (SMD = 0.61 [95% CI 0.28, 0.94], p < 0.001, I = 89.7%) though disability and pain outcomes also favored CBT intervention. Included studies demonstrated low overall bias but large heterogeneity. Sensitivity analysis demonstrated negligible study design differences and revealed moderators including CBT session frequency and final follow-up duration (p < 0.001).
Compared to usual care or alternative therapy control arms, CBT delivered the most improvement with overall quality of life and psychological outcomes. Among appropriately selected patients, CBT could improve perioperative disability, pain, quality of life, and psychological health following lumbar spine surgery.
随着越来越多的患者接受腰椎手术,新的干预措施可能会改善身心健康结果。很少有研究总结腰椎手术患者认知行为疗法(CBT)的益处。本研究收集随机对照试验数据,以调查 CBT 对腰椎手术患者报告结果的影响。
我们的研究使用了系统评价和荟萃分析的首选报告项目,并请医学图书馆专家协助在 PubMed/MEDLINE、Scopus、CINAHL、Cochrane 对照试验中心注册库、Cochrane 系统评价数据库、PsycINFO 和 Google Scholar 中进行搜索。我们计算了标准化均数差(SMD)来评估 CBT 与对照组的效果大小,并进行了敏感性分析。
我们的荟萃分析包括 7 项研究,共 531 名患者。大多数纳入的研究评估了腰椎融合术,术前由物理治疗师进行 CBT。总体生活质量(SMD=0.55 [95%CI 0.05, 1.05],p<0.001,I=86.7%)和心理结果(SMD=0.61 [95%CI 0.28, 0.94],p<0.001,I=89.7%)的效果最大,尽管残疾和疼痛结果也有利于 CBT 干预。纳入的研究总体偏倚较低,但异质性较大。敏感性分析表明,研究设计差异可以忽略不计,并揭示了一些调节因素,包括 CBT 疗程频率和最终随访时间(p<0.001)。
与常规护理或替代治疗对照组相比,CBT 在整体生活质量和心理结果方面的改善最大。在适当选择的患者中,CBT 可以改善腰椎手术后围手术期残疾、疼痛、生活质量和心理健康。