Department of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
Department of Ophthalmology, Health Sciences University of Hokkaido, Sapporo, Japan.
Ocul Immunol Inflamm. 2022 May 19;30(4):848-854. doi: 10.1080/09273948.2020.1836565. Epub 2021 Feb 11.
This study aimed to investigate the clinical features of intraocular inflammation (uveitis) in Hokkaido and to assess the etiology trends in comparison with those of our previous survey.
We retrospectively reviewed the medical records of 1,616 new referral uveitis patients (1,020 females and 596 males) in Hokkaido University Hospital between 2004 and 2014.
Sarcoidosis was the most frequent etiology (17.4%), followed by Vogt-Koyanagi-Harada disease (8.1%), Behçet's disease (4.5%), and human leukocyte antigen B27 -associated uveitis (2.5%). The etiologies in 48.7% of the patients were unclassified. Compared to the previous survey between 1994 and 2003, the rate of Behçet's disease decreased and that of sarcoidosis increased. The rates of infectious uveitis and vitreoretinal lymphoma increased.
Although the order of the top four etiologies was the same in the two surveys, the rate of sarcoidosis increased and that of Behçet's disease decreased.
本研究旨在调查北海道眼内炎症（葡萄膜炎）的临床特征，并与我们之前的调查结果进行比较，评估病因趋势。
我们回顾性分析了 2004 年至 2014 年期间在北海道大学医院就诊的 1616 例新转诊葡萄膜炎患者（1020 名女性和 596 名男性）的病历。
结节病是最常见的病因（17.4%），其次是 Vogt-Koyanagi-Harada 病（8.1%）、Behçet 病（4.5%）和人类白细胞抗原 B27 相关葡萄膜炎（2.5%）。48.7%的患者病因未分类。与 1994 年至 2003 年的上一次调查相比，Behçet 病的发生率下降，结节病的发生率上升。感染性葡萄膜炎和眼内视网膜淋巴瘤的发生率增加。
尽管两次调查的前四种病因相同，但结节病的发生率增加，而 Behçet 病的发生率下降。
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