Shree Venkatesan, Lim Tian Jin, Lean Lyn Li, So Bok Yan Jimmy, Kim Guowei
Department of Anaesthesia, National University Health System, Singapore, Singapore.
University Surgical Cluster, National University Health System, Singapore, Singapore.
Pleura Peritoneum. 2020 Nov 17;5(4):20190013. doi: 10.1515/pp-2019-0013. eCollection 2020 Nov.
Pressurised IntraPeritoneal Aerosol Chemotherapy (PIPAC) is a novel surgical technique to administer aerosolized chemotherapy into the abdominal cavity as treatment for peritoneal metastasis from various cancers. As the surgery is unique and there are concerns about occupational hazards, specific anaesthetic setup and techniques are required. Notably, our institution's experience with PIPAC has enlightened us that anaesthesia requirements during PIPAC are generally uncomplicated and that the majority of the patients undergoing PIPAC do not require invasive monitoring, advanced intra or postoperative analgesia like epidurals or PCA. The need for postoperative intensive unit care is also not required in routine PIPAC cases. We describe the anaesthetic considerations involved and the detailed preparation of staff, space, anaesthetic equipment and drugs to facilitate the appropriate modifications for anaesthesia monitoring and maintenance for an elective set up as well as our standard operating procedure for an emergency situation should it arise.
腹腔内加压雾化化疗（PIPAC）是一种新型外科技术，通过向腹腔内注入雾化化疗药物来治疗各种癌症的腹膜转移。由于该手术独特，且存在职业危害方面的担忧，因此需要特定的麻醉设置和技术。值得注意的是，我们机构在PIPAC方面的经验让我们了解到，PIPAC期间的麻醉要求通常并不复杂，大多数接受PIPAC的患者不需要有创监测、硬膜外麻醉或PCA等高级术中或术后镇痛。常规PIPAC病例也不需要术后重症监护。我们描述了所涉及的麻醉注意事项，以及工作人员、空间、麻醉设备和药物的详细准备情况，以便为择期手术的麻醉监测和维持进行适当调整，以及在紧急情况发生时我们的标准操作程序。
