Acta Orthop Belg. 2020 Sep;86(3):405-411.
C-reactive protein (CRP) distribution has been used to monitor early inflammation after total hip arthroplasty (THA). Neutrophil to lymphocyte ratio (NLR) is a new and cheap inflammatory marker. This study aimed to verify whether Neutrophil to lymphocyte ratio (NLR) distribution has an advantage when compared to C-reactive protein (CRP) distribution for the inflammation monitoring after total hip arthroplasty (THA). 116 THA patients were retrospectively selected over a 2 years period. They all had available blood tests preoperatively and at postoperative days 2, 4 and 42. Median peak values were compared between CRP and NLR. The effect of demographics on CRP and NLR was tested. At days 4 and 42, 100% and 16.3% of patients had not reached normal CRP (< 10mg/L) while 56.8% and 6.8% of patients had not reached normal NLR (<5) respectively. There was no effect of demographics on NLR except for age. Older patients had higher NLR (p 0.037). NLR showed a quicker return to normal than CRP. Our results show that NLR seems to be a better marker to follow inflammation after THA than CRP.
C-反应蛋白（CRP）分布已被用于监测全髋关节置换术（THA）后的早期炎症。中性粒细胞与淋巴细胞比值（NLR）是一种新的廉价炎症标志物。本研究旨在验证与 CRP 分布相比，NLR 分布在 THA 后炎症监测方面是否具有优势。回顾性选择了 116 例 THA 患者，时间跨度为 2 年。所有患者均在术前以及术后第 2、4 和 42 天进行了血液检查。比较 CRP 和 NLR 的中位峰值值。测试了人口统计学因素对 CRP 和 NLR 的影响。在第 4 天和第 42 天，100%和 16.3%的患者未达到正常 CRP（<10mg/L），而 56.8%和 6.8%的患者未达到正常 NLR（<5）。除年龄外，人口统计学因素对 NLR 无影响。年龄较大的患者 NLR 更高（p 0.037）。NLR 比 CRP 更快地恢复正常。我们的研究结果表明，与 CRP 相比，NLR 似乎是一种更好的 THA 后炎症标志物。
