Baddeley G M, Schomer H H, Albrecht C F
Department of Psychology, University of Cape Town.
S Afr Med J. 1988 Apr 2;73(7):409-11.
The effectiveness of freely chosen, personally paid-for, 2 mg nicotine gum (Nicorette; MPS Laboratories) as an adjunct to group psychological support in 12 heavy smokers motivated to stop was compared with 11 matched controls who chose not to use gum and received psychological support only. After 6 months, 50% of the group using gum had stopped smoking compared with 27% of the controls (verified by the measurement of carboxyhaemoglobin concentrations). There was a tendency to underuse gum despite careful instructions in its use, but surprisingly there was a significant negative correlation between the amount of gum used and stopping smoking. It is suggested that this may have been a function of the nature of the psychological support, which was highly structured to fade nicotine and build up a repertoire of alternate behaviours before stopping. In view of the tendency to underuse the gum, general practitioners prescribing nicotine gum without psychological support should ensure that sufficient gum is used for it to function as a pharmacologial aid.
对12名有戒烟意愿的重度吸烟者,将自行选择、自费购买的2毫克尼古丁口香糖(尼可戒;MPS实验室出品)作为团体心理支持的辅助手段,与11名匹配的对照组进行比较,后者选择不使用口香糖,仅接受心理支持。6个月后,使用口香糖组中有50%的人戒烟,而对照组为27%(通过测量碳氧血红蛋白浓度证实)。尽管对口香糖的使用进行了仔细指导,但仍有未充分使用的倾向,令人惊讶的是,口香糖的使用量与戒烟之间存在显著的负相关。这可能是由于心理支持的性质所致,心理支持结构严谨,旨在在戒烟前逐渐减少对尼古丁的依赖,并培养一系列替代行为。鉴于存在未充分使用口香糖的倾向,在没有心理支持的情况下开具尼古丁口香糖的全科医生应确保使用足够的口香糖,使其发挥药物辅助作用。