Angle Orthod. 2021 Jul 1;91(4):544-554. doi: 10.2319/091720-799.1.
To investigate the association between the management of mandibular arch perimeter during development of the dentition and its effects on second permanent molar (M2) eruption.
Seven electronic databases were searched without restrictions up to June 2020. Assessment was performed using the Risk Of Bias In Non-randomized Studies of Interventions (ROBINS-I) tool for non-randomized clinical trials (non-RCT). Odds ratio (OR) with 95% confidence intervals was calculated from random-effects meta-analyses. The Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) tool was used to assess the certainty of the evidence.
Five non-RCTs, with serious to moderate risk of bias, were included. A low certainty of evidence indicated that individuals undergoing mandibular arch perimeter management by controlling the position of the first molar had a high prevalence of M2 eruption difficulties. The odds of eruption disorders was 7.5 times higher (OR: 7.57, [3.72, 15.41], P < .001) in treated individuals. Subgroup analysis revealed that appliances that increased the arch perimeter lead to a greater chance of eruption disorders compared to appliances that only maintained the perimeter. The predictive factors for the M2 eruption difficulty were its previous mesioangulation in relation to the first molar (>24°) and the treatment time (>2 years).
Mandibular arch perimeter management during development of the dentition leads to an increase in the occurrence of M2 eruption difficulties. The identification of possible risk factors as well as the choice of the appropriate appliance type and the monitoring of these individuals seems to be essential to avoid undesirable effects with this therapy.
研究在牙齿发育过程中对下颌弓周长的管理及其对第二恒磨牙(M2)萌出的影响。
无限制地检索了 7 个电子数据库,检索时间截至 2020 年 6 月。使用非随机干预研究的风险偏倚评估工具(ROBINS-I)评估非随机临床试验(非 RCT)。采用随机效应荟萃分析计算比值比(OR)及其 95%置信区间。采用推荐、评估、开发和评估分级(GRADE)工具评估证据的确定性。
纳入了 5 项具有严重到中度偏倚风险的非 RCT。低确定性证据表明,通过控制第一磨牙位置来管理下颌弓周长的个体,M2 萌出困难的发生率较高。治疗组发生萌出障碍的几率高 7.5 倍(OR:7.57,[3.72,15.41],P<0.001)。亚组分析显示,增加弓周长的矫治器与仅维持周长的矫治器相比,导致萌出障碍的可能性更大。M2 萌出困难的预测因素是其与第一磨牙的先前近中向角(>24°)和治疗时间(>2 年)。
在牙齿发育过程中对下颌弓周长的管理会增加 M2 萌出困难的发生。识别可能的危险因素以及选择合适的矫治器类型并对这些个体进行监测,对于避免这种治疗的不良影响似乎是必要的。