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环绕胎盘附着部位的子宫浆膜层和肌层进行环形缝合治疗难治性产后出血。

Circular suture of the uterine serosa and myometrium layer around placental attachment site for refractory postpartum hemorrhage.

机构信息

Department of Obstetrics and Gynecology, Jianhu Hospital Affiliated to Nantong University, Jiangsu, P. R. China.

Department of Hepatobiliary Surgery, Eastern Hepatobiliary Surgery Hospital, Naval Medical University, Shanghai, P. R. China.

出版信息

J Obstet Gynaecol Res. 2021 May;47(5):1735-1742. doi: 10.1111/jog.14695. Epub 2021 Feb 15.

Abstract

OBJECTIVE

The aim of the study was to analyze the clinical outcomes of circular suture at placental attachment site for refractory postpartum hemorrhage (PPH), which could block blood supply of the serosa and myometrium layer.

METHODS

Eighty cases of refractory PPH were enrolled and retrospective analyzed in this study for further analysis from a consecutive single center database between 2010 and 2018. After undergoing circular suture of the uterine serosa and myometrium layer around placental attachment site, surgical and perioperative outcomes were recorded and analyzed.

RESULTS

Among all the patients enrolled, 28 cases (35.0%) of refractory PPH were mainly caused by uterine inertia, 36 cases (45.0%) caused by ectopic placenta, and 2 cases (2.5%) caused by coagulation disorders. After circular suture of the uterine serosa and myometrium layer at placental attachment site, all the uterine active bleeding was controlled below 40 ml without recurrence. The perioperative results were similar between the vaginal and cesarean sections groups.

CONCLUSIONS

Circular suture of the uterine serosa and myometrium at the placental attachment site could control refractory PPH with few postoperative complications. Circular suture around placenta site could be applied in time to protect the endometrium even in primary hospital.

摘要

目的

本研究旨在分析环形缝合胎盘附着部位用于治疗难治性产后出血(PPH)的临床效果,这种方法可以阻断浆膜和肌层的血液供应。

方法

本研究回顾性分析了 2010 年至 2018 年期间连续单中心数据库中 80 例难治性 PPH 患者的病例资料。对患者行胎盘附着部位子宫浆膜和肌层环形缝合后,记录并分析手术和围手术期的结果。

结果

所有纳入患者中,28 例(35.0%)难治性 PPH 主要由子宫收缩乏力引起,36 例(45.0%)由胎盘异常引起,2 例(2.5%)由凝血功能障碍引起。行胎盘附着部位子宫浆膜和肌层环形缝合后,所有患者的子宫活动性出血均控制在 40ml 以下,无复发。阴道分娩组和剖宫产组的围手术期结果相似。

结论

环形缝合胎盘附着部位的子宫浆膜和肌层可有效控制难治性 PPH,术后并发症少。即使在基层医院,也可及时行胎盘部位环形缝合术以保护子宫内膜。

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