State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, Yunnan 650201, People's Republic of China.
University of the Chinese Academy of Sciences, Beijing 100049, People's Republic of China.
J Agric Food Chem. 2021 Mar 3;69(8):2438-2443. doi: 10.1021/acs.jafc.0c07514. Epub 2021 Feb 16.
The seed oil of is extensively used as an edible oil by the nationalities of Naxi, Tibetan, and Mosuo in China, which is particularly good for beauty care and has a health protection function. A large amount of industrial waste is thrown away during the production process of seed oil. Therefore, to recover bioactive compounds from the oil residue of is environmentally friendly and economically important. For this purpose, the chemical constituents of the oil residue were investigated in our research, and five new compounds, prinsepicyanosides F-I (-) and prinamoside A (), together with 16 known compounds (-) were isolated. The structures of the new compounds (-) were unambiguously confirmed by extensive spectroscopic techniques. Preliminary pharmacological studies showed that the hydroxynitrile glucosides (, , and ) exhibited weak α-glucosidase inhibitory activity. To a certain extent, our research provides some evidence for the pharmacological function of γ-hydroxynitrile glucosides and proposes new ideas for recycling of the oil residue of .
该植物的种子油被中国的纳西族、藏族和摩梭族等民族广泛用作食用油，其具有良好的美容功效和保健功能。在种子油的生产过程中会产生大量工业废料。因此，从该植物的油渣中回收生物活性化合物在环保和经济方面都具有重要意义。为此，我们对该植物油渣的化学成分进行了研究，从中分离得到了五个新化合物（prinsepicyanosides F-I (-) 和 prinamoside A ()）和 16 个已知化合物（(-)）。通过广泛的光谱技术，明确确定了这些新化合物（(-)）的结构。初步药理研究表明，羟腈葡萄糖苷（，，和）具有较弱的α-葡萄糖苷酶抑制活性。在一定程度上，我们的研究为γ-羟腈葡萄糖苷的药理功能提供了一些证据，并为该植物油渣的回收利用提出了新的思路。
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