Juorio A V, Sloley B D
Neuropsychiatric Research Unit, University of Saskatchewan, Saskatoon, Canada.
Brain Res. 1988 Mar 22;444(2):380-2. doi: 10.1016/0006-8993(88)90951-1.
This report shows the existence of endogenous p-tyramine in the nerve cord and some organs of the lobster. Their concentrations are lower than those of dopamine or 5-hydroxytryptamine. The nerve cord levels of m-tyramine, beta-phenylethylamine and tryptamine are much lower than those of the phenolic or catecholic amines. The finding that the administration of an aromatic-L-amino acid decarboxylase inhibitor leads to a decrease of p-tyramine gives further evidence that this amine is synthesized from p-tyrosine, which is also found in high concentrations in the lobster nerve cord. The widespread distribution of p-tyramine in the nervous system and peripheral tissues of the lobster suggests that this amine may have additional roles rather than functioning only as a precursor of p-octopamine.
本报告显示龙虾的神经索和一些器官中存在内源性对酪胺。它们的浓度低于多巴胺或5-羟色胺。间酪胺、β-苯乙胺和色胺在神经索中的水平远低于酚胺或儿茶酚胺。给予芳香族-L-氨基酸脱羧酶抑制剂会导致对酪胺减少,这一发现进一步证明该胺是由对酪氨酸合成的,对酪氨酸在龙虾神经索中也大量存在。对酪胺在龙虾神经系统和外周组织中的广泛分布表明,这种胺可能具有其他作用,而不仅仅是作为对章鱼胺的前体。