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美国龙虾(美洲螯龙虾)神经索及其他一些组织中酪胺和相关单胺的存在情况。

The presence of tyramine and related monoamines in the nerve cord and some other tissues of the lobster, Homarus americanus.

作者信息

Juorio A V, Sloley B D

机构信息

Neuropsychiatric Research Unit, University of Saskatchewan, Saskatoon, Canada.

出版信息

Brain Res. 1988 Mar 22;444(2):380-2. doi: 10.1016/0006-8993(88)90951-1.

Abstract

This report shows the existence of endogenous p-tyramine in the nerve cord and some organs of the lobster. Their concentrations are lower than those of dopamine or 5-hydroxytryptamine. The nerve cord levels of m-tyramine, beta-phenylethylamine and tryptamine are much lower than those of the phenolic or catecholic amines. The finding that the administration of an aromatic-L-amino acid decarboxylase inhibitor leads to a decrease of p-tyramine gives further evidence that this amine is synthesized from p-tyrosine, which is also found in high concentrations in the lobster nerve cord. The widespread distribution of p-tyramine in the nervous system and peripheral tissues of the lobster suggests that this amine may have additional roles rather than functioning only as a precursor of p-octopamine.

摘要

本报告显示龙虾的神经索和一些器官中存在内源性对酪胺。它们的浓度低于多巴胺或5-羟色胺。间酪胺、β-苯乙胺和色胺在神经索中的水平远低于酚胺或儿茶酚胺。给予芳香族-L-氨基酸脱羧酶抑制剂会导致对酪胺减少,这一发现进一步证明该胺是由对酪氨酸合成的,对酪氨酸在龙虾神经索中也大量存在。对酪胺在龙虾神经系统和外周组织中的广泛分布表明,这种胺可能具有其他作用,而不仅仅是作为对章鱼胺的前体。

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