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女性骨盆骨折后性功能障碍:文献综述

Female Sexual Dysfunction After Pelvic Fracture: A Comprehensive Review of the Literature.

机构信息

Tulane University School of Medicine, Department of Urology, New Orleans, LA, USA.

Columbia University Medical Center, Department of Urology, New York, NY, USA.

出版信息

J Sex Med. 2021 Mar;18(3):467-473. doi: 10.1016/j.jsxm.2020.12.014. Epub 2021 Feb 13.

Abstract

BACKGROUND

Female sexual dysfunction (FSD) after pelvic fracture (PFx) has garnered little attention in the urology literature.

AIM

To review and summarize the current evidence regarding female PFx-related sexual function.

METHODS

We performed a systematic review in accordance with PRISMA guidelines, including PubMed, EMBASE, and MEDLINE. We included only English-language manuscripts and abstracts with sufficient data for inclusion. We used the search terms "female sexual dysfunction AND pelvic fracture," "sexual dysfunction AND pelvic fracture," and "female pelvic fracture AND sexual dysfunction." A total of 177 articles were identified; 41 abstracts were reviewed; of which, 19 manuscripts were reviewed. Fifteen met inclusion criteria for analysis.

OUTCOMES

The main outcome measures of this study are rates and types of female sexual dysfunction after pelvic fracture.

RESULTS

FSD is prevalent after PFx, with reported rates between 25% and 62%. Three studies used the validated Female Sexual Function Index. The other 12 used non-validated questionnaires or adapted quality-of-life questionnaires with specific questions regarding FSD. The most common complaints include difficulty with intercourse, dyspareunia, orgasmic dysfunction, genitourinary pain, decreased interest in intercourse, decreased satisfaction with intercourse, and pelvic floor dysfunction. Only 1 study addressed resolution of dysfunction (30 of 98 patients [30.4%]).

CLINICAL IMPLICATIONS

FSD is prevalent and an under-recognized sequela of pelvic fracture. This requires future prospective study to better characterize sexual dysfunction and identify effective treatments in trauma survivors.

STRENGTH AND LIMITATIONS

To Increase awareness of FSD after pelvic trauma and the impact on the quality of life in trauma survivors. The current literature is limited by a lack of standardized assessment of FSD, limited follow-up, and minimal discussion of treatment options, in addition to the inherent bias of retrospective studies.

CONCLUSIONS

FSD after traumatic PFx is not uncommon, occurs mostly in young women, and can be morbid. FSD after PFx is underreported in the urology literature. Thus, all female PFx patients should be screened for FSD by validated questionnaires. The published literature offers little knowledge as to the epidemiology, evaluation, definition, and potential treatments of FSD after PFx. Prospective studies are needed to better understand female sexual function in trauma survivors and the potential methods for prevention and rehabilitation, all within the context of a multidisciplinary approach. Walton AB, Leinwand GZ, Raheem O, et al. Female Sexual Dysfunction After Pelvic Fracture: A Comprehensive Review of the Literature. J Sex Med 2021;18:467-473.

摘要

背景

骨盆骨折(PFx)后女性性功能障碍(FSD)在泌尿外科文献中很少受到关注。

目的

综述和总结目前关于女性 PFx 相关性功能的证据。

方法

我们按照 PRISMA 指南进行了系统评价,包括 PubMed、EMBASE 和 MEDLINE。我们仅纳入了有足够数据纳入的英文文献和摘要。我们使用了以下搜索词:“女性性功能障碍和骨盆骨折”、“性功能障碍和骨盆骨折”以及“女性骨盆骨折和性功能障碍”。共确定了 177 篇文章,其中 41 篇摘要进行了审查,其中 19 篇进行了全文审查。15 篇符合分析纳入标准。

主要结局指标

本研究的主要结局指标是骨盆骨折后女性性功能障碍的发生率和类型。

结果

PFx 后 FSD 很常见,报道的发生率为 25%至 62%。三项研究使用了经过验证的女性性功能指数。另外 12 项研究使用了未经验证的问卷或改编的生活质量问卷,其中包含特定的 FSD 问题。最常见的抱怨包括性交困难、性交疼痛、性高潮障碍、泌尿生殖系统疼痛、性交兴趣减退、性交满意度下降和盆底功能障碍。只有 1 项研究探讨了性功能障碍的解决情况(98 例患者中的 30 例[30.4%])。

临床意义

FSD 很常见,是骨盆骨折的一种未被认识到的后遗症。这需要未来的前瞻性研究来更好地描述创伤幸存者的性功能障碍,并确定有效的治疗方法。

局限性

提高对骨盆创伤后 FSD 的认识,并认识到对创伤幸存者生活质量的影响。目前的文献受到缺乏标准化 FSD 评估、随访有限以及对治疗选择的讨论很少的限制,此外还存在回顾性研究的固有偏倚。

结论

创伤性 PFx 后 FSD 并不少见,主要发生在年轻女性,可能会导致疾病恶化。PFx 后 FSD 在泌尿外科文献中报道较少。因此,所有女性 PFx 患者都应通过经过验证的问卷进行 FSD 筛查。目前的文献对于 PFx 后 FSD 的流行病学、评估、定义和潜在治疗方法知之甚少。需要前瞻性研究来更好地了解创伤幸存者的女性性功能,以及预防和康复的潜在方法,所有这些都需要在多学科方法的背景下进行。Walton AB、Leinwand GZ、Raheem O 等人。骨盆骨折后女性性功能障碍:文献综述。性医学杂志 2021;18:467-473。

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