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一名幼儿的松果体区脑膜瘤

Pineal Region Meningioma in a Very Young Child.

作者信息

Gendle Chandrashekhar, Karthigeyan Madhivanan, Salunke Pravin

机构信息

Department of Neurosurgery, Postgraduate Institute of Medical Education & Research (PGIMER), Chandigarh, India.

Department of Neurosurgery, Postgraduate Institute of Medical Education & Research (PGIMER), Chandigarh, India,

出版信息

Pediatr Neurosurg. 2021;56(1):73-78. doi: 10.1159/000513406. Epub 2021 Feb 17.

Abstract

INTRODUCTION

Meningiomas in childhood are infrequently seen. Furthermore, they are extremely rare at a pineal location with few reported cases above 5-years of age. We present a very young child with a large pineal region meningioma which mimicked the usually occurring pathologies at this site.

CASE PRESENTATION

A 2.5-year-old child presented with symptoms of raised intracranial pressure. MRI demonstrated a homogenously enhancing pineal lesion with small cystic areas. After an initial cerebrospinal fluid evaluation for germ cell tumors, the child underwent excision of the lesion by the Krause approach. The tumor showed no definitive dural attachment, had well-defined arachnoid interface, and was completely excised. The final histopathology was meningioma.

CONCLUSION

Although unusual, we highlight the importance of considering meningiomas among the childhood pineal region lesions, given their good outcome with total resection. Also, pertinent brief literature of the pediatric pineal region meningiomas has been provided. An assessment of preoperative and intraoperative features (clear arachnoid plane) along with adjuncts such as frozen studies can help discern various entities of this region, and decide the extent of excision.

摘要

引言

儿童脑膜瘤较为少见。此外,松果体区的脑膜瘤极为罕见,5岁以上报道的病例很少。我们报告一例非常年幼的儿童患有巨大的松果体区脑膜瘤,该肿瘤表现类似于该部位常见的病变。

病例介绍

一名2.5岁儿童出现颅内压升高症状。磁共振成像(MRI)显示松果体区有一个均匀强化的病变,伴有小的囊性区域。在对生殖细胞肿瘤进行初步脑脊液评估后,该儿童通过克劳斯(Krause)入路切除了病变。肿瘤未显示明确的硬膜附着,蛛网膜界面清晰,且完全切除。最终组织病理学检查为脑膜瘤。

结论

尽管不常见,但鉴于完全切除后预后良好,我们强调在儿童松果体区病变中考虑脑膜瘤的重要性。此外,还提供了有关儿童松果体区脑膜瘤的相关简短文献。术前和术中特征(清晰的蛛网膜平面)评估以及冰冻切片等辅助检查有助于鉴别该区域的各种病变,并确定切除范围。

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