Giuffrida Gaetano, Markovic Uros, Parisi Marina, Nicolosi Daniela, Calafiore Valeria
Division of Hematology AOU "Policlinico - Vittorio Emanuele" Catania Italy.
Department of General Surgery and Medical-Surgical Specialties, Hematology Section University of Catania Catania Italy.
Clin Case Rep. 2020 Dec 3;9(2):638-643. doi: 10.1002/ccr3.3588. eCollection 2021 Feb.
Acquired hemophilia should be evaluated in pediatric patients with bleeding and isolated prolonged aPTT. Immunosuppressive treatment should be initiated even in minor bleedings. Bypassing agents like rFVIIa can be used in children with success.
对于有出血症状且活化部分凝血活酶时间(aPTT)单独延长的儿科患者,应评估是否患有获得性血友病。即使是轻微出血,也应开始免疫抑制治疗。旁路制剂如重组活化凝血因子VII(rFVIIa)可成功用于儿童患者。