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双侧颌下腺弥漫大 B 细胞淋巴瘤和甲状腺黏膜相关淋巴组织淋巴瘤—一种罕见的共存。

DLBCL of bilateral submandibular glands and MALToma of thyroid-A rare coexistence.

机构信息

Department of Pathology, Maulana Azad Medical College, New Delhi, India.

Department of ENT, Maulana Azad Medical College, New Delhi, India.

出版信息

Cytopathology. 2021 Jul;32(4):523-526. doi: 10.1111/cyt.12960. Epub 2021 Mar 16.

Abstract

Involvement of the bilateral submandibular glands and thyroid by the same lymphoma simultaneously has been reported in the literature. However, two different types of lymphomas presenting simultaneously at different sites have never been reported. This case report highlights this rare occurrence. A 65-year-old female, a known case of Hashimoto's thyroiditis with raised anti-TPO antibodies, presented with thyroid swelling for 1 year and bilateral submandibular swelling for 3 years. FNAC and flow cytometry showed features of mucosa-associated lymphoid tissue lymphoma in the thyroid gland, whereas the bilateral submandibular glands showed features of diffuse large B cell lymphoma. Histopathology and immunohistochemistry from the submandibular swelling led to similar diagnoses as the flow cytometry.

摘要

文献中曾报道过双侧颌下腺和甲状腺同时被同一种淋巴瘤累及的情况。然而,两种不同类型的淋巴瘤同时在不同部位出现的情况从未有报道过。本病例报告强调了这种罕见的情况。一位 65 岁女性,患有桥本甲状腺炎,抗 TPO 抗体升高,因甲状腺肿胀 1 年和双侧颌下腺肿胀 3 年就诊。FNAC 和流式细胞术显示甲状腺的黏膜相关淋巴组织淋巴瘤特征,而双侧颌下腺则显示弥漫性大 B 细胞淋巴瘤特征。来自颌下腺肿胀的组织病理学和免疫组织化学检查得出了与流式细胞术相似的诊断结果。

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