Department of Dermatology, Children's Hospital of Fudan University, Shanghai, China.
Department of Dermatology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Int J Infect Dis. 2021 Apr;105:349-350. doi: 10.1016/j.ijid.2021.02.051. Epub 2021 Feb 16.
Cutaneous secondary syphilis presents with various manifestations, including condyloma lata (confluented moist papules). This article reports an unusual case of oral condyloma lata. A 56-year-old man presented with a 2-month history of foreign body sensation and sore throat. Physical examination revealed a hypertrophic, reddish-brown, flat-topped, moist plaque in the right amygdaloid fossa. This raised clinical suspicion of lymphoma. However, further enquiry revealed that the patient had extramarital sexual history with a female sex worker. Rapid plasma regain and Treponema pallidum particle agglutination tests were both positive. The patient's wife was diagnosed with early latent syphilis. Both the patient and his wife were treated with penicillin G benzathine, and the lesion in the male patient disappeared in 2 weeks. To the authors' knowledge, a single condyloma lata in the amygdaloid fossa mimicking lymphoma has not been reported previously. Awareness of the usual manifestations of syphilis can avoid unnecessary biopsy, and early diagnosis and treatment may prevent irreversible complications. Partner notification is very important to reduce the risk of transmission, and persistent or recurrent infection.
二期梅毒皮肤损害可呈现多种表现，包括扁平湿疣（融合性湿润丘疹）。本文报告 1 例口腔扁平湿疣的不典型病例。1 例 56 岁男性，因异物感和咽痛 2 个月就诊。体格检查发现右侧扁桃体窝有 1 个肥厚的、红棕色、平顶、湿润斑块。该表现高度提示淋巴瘤。但进一步询问病史发现，患者有婚外性行为，性伴侣为性工作者。快速血浆反应素环状卡片试验和梅毒螺旋体颗粒凝集试验均为阳性。患者的妻子被诊断为早期潜伏梅毒。患者和其妻子均接受了苄星青霉素治疗，2 周后男性患者的皮损消失。据作者所知，此前尚未报道过单侧扁桃体窝的扁平湿疣样损害酷似淋巴瘤。了解梅毒的常见表现有助于避免不必要的活检，早期诊断和治疗可预防不可逆的并发症。通知性伴侣对于降低传播风险和持续或复发感染非常重要。
