Chang Nai-Yuan, Zhu Yihua, Curtis Donald, Le Oanh, Yang Vincent, Fried William A, Simon Jacob C, Banan Prajna, Darling Cynthia L, Fried Daniel
University of California, San Francisco, San Francisco, CA 94143-0758.
Proc SPIE Int Soc Opt Eng. 2020 Feb;11217. doi: 10.1117/12.2550982. Epub 2020 Feb 19.
New imaging technologies are needed for the clinical assessment of lesions on root surfaces. It is not sufficient to simply detect caries lesions; methods are needed to assess lesion depth, structural composition and activity to determine if chemical intervention has the potential to be effective and if remineralization has occurred. Lesions were monitored using CP-OCT during lesion dehydration to assess the lesion structure and any shrinkage. Thermal imaging at 6-10 m wavelengths and short wavelength-IR imaging at 1450-1750-nm were used to monitor thermal emission during lesion dehydration to assess lesion activity. Imaging probes were custom fabricated for clinical use. We present the first clinical results of a small feasibility study employing CP-OCT, thermal and SWIR imaging to assess lesion activity on thirty test subjects with suspected root caries lesions.
临床评估牙根表面的病变需要新的成像技术。仅仅检测到龋损是不够的；需要有方法来评估病损深度、结构组成和活性，以确定化学干预是否有可能有效以及是否发生了再矿化。在病损脱水过程中使用共焦偏振光学相干断层扫描（CP-OCT）监测病损，以评估病损结构和任何收缩情况。利用6-10米波长的热成像和1450-1750纳米的短波红外成像来监测病损脱水过程中的热发射，以评估病损活性。成像探头是为临床使用而定制制造的。我们展示了一项小型可行性研究的首批临床结果，该研究采用CP-OCT、热成像和短波红外成像来评估30名疑似根龋病变测试对象的病损活性。
