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婴儿腹部手术后切口疝:发生率及危险因素的回顾性分析。

Incisional hernia after abdominal surgery in infants: A retrospective analysis of incidence and risk factors.

机构信息

Emma Children's Hospital, Amsterdam UMC, University of Amsterdam and Vrije Universiteit Amsterdam, Department of Paediatric Surgery, Amsterdam, Netherlands; Tytgat Institute for Liver and Intestinal Research, Amsterdam UMC, University of Amsterdam, Netherlands; Medical Library, Vrije Universiteit, Amsterdam, Netherlands.

Emma Children's Hospital, Amsterdam UMC, University of Amsterdam and Vrije Universiteit Amsterdam, Department of Paediatric Surgery, Amsterdam, Netherlands; Medical Library, Vrije Universiteit, Amsterdam, Netherlands.

出版信息

J Pediatr Surg. 2021 Nov;56(11):2107-2112. doi: 10.1016/j.jpedsurg.2021.01.037. Epub 2021 Feb 10.

Abstract

PURPOSE

Incisional hernia (IH) is a complication following abdominal surgery extensively studied in adults but less so in infants. This study aimed to identify the incidence, high risk diseases and risk factors of IH following abdominal surgery in infants.

METHODS

Infants undergoing abdominal surgery before the age of three years in our tertiary centre between 1998 and 2018 were included. Patient demographics, peri‑operative details and the course during follow up were retrospectively extracted from patient records. Multivariate logistic regression was performed to identify risk factors.

RESULTS

The incidence of incisional hernia was 5.2% (107/2055). Necrotizing enterocolitis (12%), gastroschisis (19%), and omphalocele (17%) had the highest incidences of IH. Wound infection (OR: 5.3, 95%-CI:2.9-9.5), preterm birth (OR: 4.2, 95%-CI:2.6-6.7) and history of stoma (OR 1.7, 95%-CI:1.1-2.8) were significant risk factors for IH. Whilst age at surgery, surgical approach and total number of operations did not significantly influence IH development. The IH resolved in 15% (16/107) without surgery.

CONCLUSION

One in twenty infants experiences IH following abdominal surgery, which is higher than previously described. Understanding the incidence of IH and associated risk factors will allow physicians to identify infants that may be at increased risk for IH and to possibly act pre-emptively.

摘要

目的

切口疝(IH)是腹部手术后的一种并发症,在成人中广泛研究,但在婴儿中研究较少。本研究旨在确定婴儿腹部手术后 IH 的发生率、高风险疾病和危险因素。

方法

纳入 1998 年至 2018 年期间在我们的三级中心接受三岁以下腹部手术的婴儿。从患者病历中回顾性提取患者人口统计学、围手术期详细信息和随访过程。采用多变量逻辑回归分析识别危险因素。

结果

切口疝的发生率为 5.2%(107/2055)。坏死性小肠结肠炎(12%)、腹裂(19%)和脐膨出(17%)的 IH 发生率最高。伤口感染(OR:5.3,95%CI:2.9-9.5)、早产(OR:4.2,95%CI:2.6-6.7)和造口史(OR:1.7,95%CI:1.1-2.8)是 IH 的显著危险因素。手术时年龄、手术方式和手术总数均与 IH 发展无显著相关性。15%(16/107)的 IH 无需手术即可自行缓解。

结论

每 20 名接受腹部手术的婴儿中就有 1 名发生 IH,高于先前描述的发生率。了解 IH 的发生率和相关危险因素将使医生能够识别出可能存在 IH 风险增加的婴儿,并可能提前采取行动。

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