Department of Orthopaedic Surgery, Juntendo University School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.
Int Orthop. 2021 May;45(5):1169-1177. doi: 10.1007/s00264-021-04994-7. Epub 2021 Feb 22.
Cortical hypertrophy (CH) after total hip arthroplasty (THA) is thought as a process of femoral cortical functional adaptation against the stem. However, no study has been performed to investigate the association between CH and femoral head size. The purpose of this study is to investigate the factors related to femoral CH around the cementless stem after THA.
THAs in 31 patients using 36-mm metal head and as a control, age-matched 62 THAs with 32-mm metal head have been analyzed. Radiographs were reviewed at four years to determine cortical thickness change from immediate post-operative one. Pre-operative and immediate post-operative radiographs were used to calculate the femoral morphology, canal fill ratio, stem alignment, and femoral and acetabular offset. Univariate and multivariate logistic regression analyses were performed to identify the risk factors for CH.
Patients with a 36-mm metal head had a significantly higher rate of severe CH (P = 0.001) than those with a 32-mm metal head. The multivariate logistic regression analysis with dependent variables of CH showed that the use of a 36-mm metal head had a significantly positive effect on CH. The odds ratio of a 36-mm metal head in mild CH was 2.517 (95% confidence interval, 1.032-6.143; P = 0.043), and that in severe CH was 8.273 (95% confidence interval, 2.679-25.551; P = 0.000). Age and the canal flare index were weakly and negatively influenced by mild CH.
The use of a 36-mm metal head was the dominant risk factor for CH.
全髋关节置换术后(THA)的皮质增厚(CH)被认为是股骨皮质对柄的功能适应过程。然而,目前尚无研究探讨 CH 与股骨头大小之间的关系。本研究旨在探讨 THA 后无骨水泥柄周围 CH 与股骨的相关因素。
分析了 31 例使用 36mm 金属头的 THA 患者(研究组)和 62 例年龄匹配的使用 32mm 金属头的 THA 患者(对照组)。在术后 4 年时通过 X 线片评估皮质厚度的变化。使用术前和术后即刻 X 线片计算股骨形态、髓腔填充比、柄的对线和股骨与髋臼的偏心距。采用单因素和多因素逻辑回归分析确定 CH 的危险因素。
研究组使用 36mm 金属头的患者发生严重 CH 的比例明显高于对照组(P = 0.001)。多因素逻辑回归分析中,CH 的因变量是使用 36mm 金属头,结果表明使用 36mm 金属头对 CH 有显著的正向影响。在轻度 CH 中,36mm 金属头的优势比为 2.517(95%置信区间为 1.032-6.143;P = 0.043),在重度 CH 中为 8.273(95%置信区间为 2.679-25.551;P = 0.000)。年龄和髓腔开口指数对轻度 CH 有微弱的负向影响。
使用 36mm 金属头是 CH 的主要危险因素。