Catalysis and Integrated Research Group, RIKEN Center for Sustainable Resource Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
Org Biomol Chem. 2021 Mar 18;19(10):2096-2109. doi: 10.1039/d0ob02349c.
Diacyl peroxides, (RCO2)2, are readily available and widely used reagents for organic synthesis, because they can serve as electrophiles, oxidants, and radical sources. Recently, they have been used extensively as sources of O- and C-functional groups, in contrast to their classical applications as radical initiators. These novel reaction modes have greatly expanded the synthetic utility of diacyl peroxides by making it possible to simultaneously utilize plural functionalities of diacyl peroxides in unprecedented ways, with or without the aid of transition-metal catalysts. Here, we review recent advances in reactions utilizing diacyl peroxides as O- and C-sources, with examples illustrating how the reactivity of diacyl peroxides in organic reactions can be controlled.
过氧二羧酸酯，（RCO2）2，是一种易得且用途广泛的有机合成试剂，因为它们可以作为亲电试剂、氧化剂和自由基源。最近，它们已被广泛用作 O 和 C 官能团的来源，与它们作为自由基引发剂的经典应用形成对比。这些新颖的反应模式通过使有可能以以前所未有的方式同时利用过氧二羧酸酯的多种官能团，从而极大地扩展了过氧二羧酸酯的合成用途，而无需或无需过渡金属催化剂的帮助。在这里，我们综述了利用过氧二羧酸酯作为 O 和 C 源的反应的最新进展，通过实例说明了如何控制过氧二羧酸酯在有机反应中的反应性。
