Lynn B, Shakhanbeh J
Department of Physiology, University College London, U.K.
Neurosci Lett. 1988 Feb 15;85(1):71-6. doi: 10.1016/0304-3940(88)90431-4.
Forty-three high threshold mechanoreceptors (HTMs) with myelinated fibres were characterized in hairy and glabrous skin of the hind limb of the rat. Mechanical thresholds and conduction velocities were similar in both skin areas. The behaviour of 15 hairy and 14 glabrous skin HTMs were studied in response to repeated heating to 55-60 degrees C. Responses to heating were either very weak or absent, except for two units, one from each group, that fired on second and subsequent heat trials. A delta-HTMs in rat skin, either hairy or glabrous, are thus much less easily excited by heat than are similar units in rabbit, cat or monkey skin. C-fibres in rat skin are known to respond well to heating, and therefore provide the only significant input about noxious heat in this species.
在大鼠后肢的有毛皮肤和无毛皮肤中，对43个具有髓鞘纤维的高阈值机械感受器（HTM）进行了特征描述。两个皮肤区域的机械阈值和传导速度相似。研究了15个有毛皮肤和14个无毛皮肤HTM对重复加热至55 - 60摄氏度的反应。除了每组各有一个单位在第二次及后续热刺激试验中放电外，对加热的反应非常微弱或无反应。因此，大鼠皮肤中的Aδ-HTM，无论是有毛还是无毛的，都比兔、猫或猴皮肤中的类似单位更不容易被热激发。已知大鼠皮肤中的C纤维对加热反应良好，因此是该物种中关于有害热的唯一重要输入。
