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[全球肺癌筛查指南与共识的质量评估]

[Quality assessment of global lung cancer screening guidelines and consensus].

作者信息

Shi Y J, Li J, Meng Y H, Xiang L, Yan R J, Zhan Y L, Yue H X, Jiang Y, Li N, Zhang J, He J

机构信息

School of Population Medicine and Public Health, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.

Office of Cancer Screening, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 2021 Feb 10;42(2):241-247. doi: 10.3760/cma.j.cn112338-20200806-01035.

Abstract

To understand the research progress and quality of lung cancer screening guidelines and consensus in China and abroad, and to provide reference for the formulation of high-quality lung cancer screening guidelines in China. Databases including PubMed, Medline, Embase, Cochrane Library, Web of Science, China National Knowledge Infrastructure, SinoMed, VIP and Wanfang Data were searched, websites and important references were also searched by hand retrieval. The Appraisal of Guidelines for Research & Evaluation Ⅱ(AGREE Ⅱ) and Reporting Items for Practice Guidelines in Healthcare (RIGHT) were used to assess the quality of newly published or updated guidelines and consensus. A total of 9 guidelines and consensus published between 2015 and 2020 were included in this study, with countries including the United States, China, Canada, Saudi Arabia and South Africa. The field of scope and purpose and clarity of presentation scored relatively high but the rigor of development and applicability scored low. Five guidelines were judged to be A-level, all of which were published abroad, and the remaining four were B-level, including three guidelines and consensus issued by China and 1 guideline issued by South Africa. The report rate of RIGHT were higher in basic information and background, lower in review and quality assurance, funding and declaration and management of interests. There were 5 guidelines with a good level and 4 guidelines and consensus with a moderate level. The best overall quality guidelines were those published by the American College of Chest Physicians in 2018 and by the Canadian Task Force on Preventive Health Care in 2016. The number of countries and institutions that issue lung cancer screening guidelines and consensus had been increasing gradually, but the quality in China remained low. It is necessary to develop high-quality lung cancer screening guidelines suitable for China's national conditions in combination with evidence-based methods to guide practice.

摘要

了解国内外肺癌筛查指南与共识的研究进展及质量,为我国制定高质量肺癌筛查指南提供参考。检索了包括PubMed、Medline、Embase、Cochrane图书馆、Web of Science、中国知网、中国生物医学文献数据库、维普和万方数据在内的数据库,并通过手工检索网站和重要参考文献。采用《指南研究与评价Ⅱ》(AGREEⅡ)和《医疗保健实践指南报告条目》(RIGHT)对新发布或更新的指南与共识进行质量评估。本研究共纳入2015年至2020年间发表的9项指南与共识,涉及美国、中国、加拿大、沙特阿拉伯和南非等国家。范围和目的领域以及表述清晰度得分相对较高,但制定的严谨性和适用性得分较低。5项指南被判定为A级,均在国外发表,其余4项为B级,包括中国发布的3项指南与共识和南非发布的1项指南。RIGHT在基本信息和背景方面的报告率较高,在审查与质量保证、资金与利益声明及管理方面的报告率较低。有5项指南水平良好,4项指南与共识水平中等。总体质量最佳的指南是美国胸科医师学会2018年发布的和加拿大预防性医疗保健工作组2016年发布的。发布肺癌筛查指南与共识的国家和机构数量在逐渐增加,但我国的质量仍较低。有必要结合循证方法制定适合我国国情的高质量肺癌筛查指南以指导实践。

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