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威斯康星州儿童上呼吸道症状调查:特定疾病生活质量工具的验证。

Wisconsin Upper Respiratory Symptom Survey for Kids: Validation of an Illness-specific Quality of Life Instrument.

机构信息

Department of Pediatrics, Division of Infectious Diseases, University of Wisconsin-Madison, Madison, WI, USA.

Research Design & Statistics Unit, University of Wisconsin-Madison School of Nursing, Madison, WI, USA.

出版信息

Pediatr Res. 2021 Dec;90(6):1207-1214. doi: 10.1038/s41390-021-01395-9. Epub 2021 Feb 24.

Abstract

BACKGROUND

Acute respiratory infections (ARIs) are the most common illness seen in the pediatric ambulatory setting. Research in this area is hampered by the lack of validated ARI measures. The aim of this study was to assess the reliability and validity of the Wisconsin Upper Respiratory Symptom Survey for Kids (WURSS-K), a 15-item instrument, which measures illness-specific symptoms and impact on quality of life during an ARI.

METHODS

WURSS-K was administered to two populations: (1) children aged 4-10 years recruited from the local community and (2) 9- and 10-year-old children from an ongoing study, the Urban Environment and Childhood Asthma.

RESULTS

Overall, 163 children with 249 ARI episodes completed WURSS-K. WURSS-K was analyzed using multiple models to evaluate reliability and validity for a two-factor structure (symptom and functionality) and a single global structure. These models provided evidence of reliability and validity with omega of 0.72 and 0.91 for symptoms and functionality along with the single structure with omega of 0.90.

CONCLUSIONS

WURSS-K shows strong psychometric properties for validity and reliability as either a single global factor or a two-factor structure. This instrument will be useful in both therapeutic trials and observational studies among children with ARI in ambulatory settings.

IMPACT

WURSS-K is a valid and reliable illness-specific quality of life instrument that evaluates the impacts of ARIs on children. WURSS-K is designed for children 4-10 years of age, for whom there is a lack of validated assessment tools. This now validated instrument will be useful for future observational studies and therapeutic trials among children with ARIs in ambulatory settings.

摘要

背景

急性呼吸道感染(ARI)是儿科门诊最常见的疾病。该领域的研究受到缺乏经过验证的ARI 测量方法的阻碍。本研究的目的是评估威斯康星州上呼吸道症状儿童调查(WURSS-K)的可靠性和有效性,这是一种 15 项的工具,用于测量ARI 期间疾病特异性症状和对生活质量的影响。

方法

WURSS-K 被应用于两个人群:(1)从当地社区招募的 4-10 岁儿童;(2)正在进行的 Urban Environment and Childhood Asthma 研究中的 9-10 岁儿童。

结果

共有 163 名儿童的 249 次 ARI 发作完成了 WURSS-K。使用多种模型对 WURSS-K 进行了分析,以评估其用于两种因素结构(症状和功能)和单一全局结构的可靠性和有效性。这些模型提供了可靠性和有效性的证据,症状和功能的 omega 为 0.72 和 0.91,以及具有 0.90 的单个结构的 omega。

结论

WURSS-K 具有良好的信度和效度,可作为单一的全局因子或两种因子结构。该工具将在儿科门诊中治疗试验和观察性研究中都很有用。

意义

WURSS-K 是一种评估 ARI 对儿童影响的有效的、可靠的疾病特异性生活质量工具。WURSS-K 专为 4-10 岁儿童设计,因为缺乏经过验证的评估工具。这个经过验证的工具将对未来在儿科门诊中治疗 ARI 的观察性研究和治疗试验有用。

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