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失眠症认知行为治疗对原发性失眠患者主观-客观睡眠差异的影响:一项小规模队列初步研究。

Effects of Cognitive Behavioral Therapy for Insomnia on Subjective-Objective Sleep Discrepancy in Patients with Primary Insomnia: a Small-Scale Cohort Pilot Study.

机构信息

Department of Psychiatry, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga, 520-2192, Japan.

Japan CBT Center, CG building F4, 3-12 Chuo-cho, Hikone, Shiga, 522-0063, Japan.

出版信息

Int J Behav Med. 2021 Dec;28(6):715-726. doi: 10.1007/s12529-021-09969-x. Epub 2021 Feb 24.

Abstract

BACKGROUND

Cognitive behavioral therapy for insomnia (CBT-I) is a first-line therapy for insomnia disorders. We assessed changes in discrepancies between subjective and objective sleep measures and correlations between discrepancy changes and clinical insomnia severity for CBT-I in patients with primary insomnia METHODS: Fifty-two outpatients (mean age, 60.3 years; 26 women) with primary insomnia were treated by individual CBT-I (50 min, maximum six sessions, once every 1-2 weeks). One week before and after CBT-I, patients recorded a sleep log and wore an actigraphy device. Subjective and objective time in bed (TIB), total sleep time (TST), sleep-onset latency (SOL), wake time after sleep onset (WASO), and sleep efficiency (SE) were evaluated by averaging 1-week records. Relative values of sleep discrepancy in TIB, TST, SOL, WASO, and SE were calculated for estimating effects of CBT-I. The therapeutic effects were also evaluated using psychological scales before and after CBT-I.

RESULTS

Subjective and objective discrepancies in sleep measures decreased by 36, 25, and 37 min in TST, SOL, and WASO, respectively, and 7% in SE (all P < 0.001) after CBT-I. Seven patients transitioned from underestimating SE before CBT-I to overestimating SE after CBT-I. Although CBT-I improved relative values of discrepancy in WASO and SE, alongside ISI, the improvement in insomnia severity only correlated with SOL discrepancy.

CONCLUSIONS

CBT-I may reduce the discrepancy between subjective and objective sleep measures in patients with primary insomnia. However, a greater therapeutic effect of CBT-I was observed in reducing the ISI, which was slightly influenced by improvements in sleep discrepancies.

摘要

背景

认知行为疗法治疗失眠症(CBT-I)是失眠症的一线治疗方法。我们评估了原发性失眠症患者 CBT-I 治疗前后主观和客观睡眠测量结果之间的差异变化以及差异变化与临床失眠严重程度之间的相关性。

方法

52 名原发性失眠症门诊患者(平均年龄 60.3 岁,女性 26 名)接受了个体 CBT-I 治疗(50 分钟,最多 6 次,每 1-2 周一次)。在 CBT-I 治疗前后一周,患者记录睡眠日志并佩戴活动记录仪。通过平均 1 周的记录来评估主观和客观的卧床时间(TIB)、总睡眠时间(TST)、入睡潜伏期(SOL)、睡眠后觉醒时间(WASO)和睡眠效率(SE)。计算 TIB、TST、SOL、WASO 和 SE 中睡眠差异的相对值,以估计 CBT-I 的效果。在 CBT-I 前后还使用心理量表评估治疗效果。

结果

CBT-I 治疗后 TST、SOL 和 WASO 的主观和客观睡眠差异分别减少了 36、25 和 37 分钟,SE 提高了 7%(均 P<0.001)。7 名患者在 CBT-I 治疗前 SE 低估转变为治疗后 SE 高估。尽管 CBT-I 改善了 WASO 和 SE 的相对差异,但与 ISI 一起,失眠严重程度的改善仅与 SOL 差异相关。

结论

CBT-I 可能会减少原发性失眠症患者主观和客观睡眠测量结果之间的差异。然而,CBT-I 的治疗效果更大,表现在降低 ISI,这受到睡眠差异改善的轻微影响。

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