Chatterjee Srirup, Bansal Nikhil, Ghosh Rajarshi, Sankhyan Lakshmi Kumari, Chatterjee Sujoy, Pandey Santosh, Bose Satyajit
The Mission Hospital, Durgapur, West Bengal India.
Indian J Thorac Cardiovasc Surg. 2021 Mar;37(2):175-182. doi: 10.1007/s12055-020-00925-0. Epub 2020 Mar 25.
Rheumatic heart disease is the most common acquired heart disease in children in developing countries. The heart valve lesions produce severe hemodynamic changes due to scarring of the valves over time. Around 15.6 million people are affected by rheumatic heart disease (RHD), and 230,000 die around the globe annually. Valve repair should be the primary goal, although it is technically challenging because of the fact that rheumatic process evolves making repair outcomes variable.
We reviewed the literature for the various techniques done for mitral valve repair in children with rheumatic heart disease. Early and late results of repair were compared with the results found for mitral valve repair done for such children.
Prosthetic heart valve implantation in children has major negative impact on their immediate- and long-term survival as well as on quality of their life. Valve repair is associated with improved ventricular function because the normal valve tissue and subvalvular apparatus are preserved, reduced complications related to prosthetic valve, and lower in-hospital and late mortality.
In children, the results of mitral valve replacement were found to be inferior to those of mitral valve repair. The reoperation rates are similar in patients undergoing initial repair or replacement, which favors repair as an option. In developing world, rheumatic mitral valve disease is more prevalent where adequate facilities for monitoring of prosthetic valve function and management of anticoagulation therapy are not easily available. Valve repair therefore should be the primary goal.
风湿性心脏病是发展中国家儿童中最常见的后天性心脏病。随着时间推移,心脏瓣膜病变会因瓣膜瘢痕形成而产生严重的血流动力学变化。全球约有1560万人受风湿性心脏病(RHD)影响,每年有23万人死亡。瓣膜修复应是主要目标,尽管由于风湿过程不断发展导致修复结果不一,使得瓣膜修复在技术上具有挑战性。
我们查阅了有关风湿性心脏病患儿二尖瓣修复所采用的各种技术的文献。将修复的早期和晚期结果与针对此类患儿进行二尖瓣修复的结果进行比较。
儿童人工心脏瓣膜植入对其近期和长期生存以及生活质量有重大负面影响。瓣膜修复与心室功能改善相关,因为正常瓣膜组织和瓣下结构得以保留,与人工瓣膜相关的并发症减少,住院死亡率和晚期死亡率降低。
在儿童中,二尖瓣置换的结果不如二尖瓣修复。初次修复或置换患者的再次手术率相似,这使得修复成为一个更优选择。在发展中世界,风湿性二尖瓣疾病更为普遍,那里不易获得监测人工瓣膜功能和管理抗凝治疗的充足设施。因此,瓣膜修复应是主要目标。