Joint Department of Biomedical Engineering, The University of North Carolina at Chapel Hill and North Carolina State University, Chapel Hill, North Carolina, U.S.
Divers Alert Network, Durham, North Carolina, U.S.
Undersea Hyperb Med. 2021 First Quarter;48(1):59-72. doi: 10.22462/01.03.2021.8.
It is widely accepted that bubbles are a necessary but insufficient condition for the development of decompression sickness. However, open questions remain regarding the precise formation and behavior of these bubbles after an ambient pressure reduction (decompression), primarily due to the inherent difficulty of directly observing this phenomenon in vivo. In decompression research, information about these bubbles after a decompression is gathered via means of ultrasound acquisitions. The ability to draw conclusions regarding decompression research using ultrasound is highly influenced by the variability of the methodologies and equipment utilized by different research groups. These differences play a significant role in the quality of the data and thus the interpretation of the results. The purpose of this review is to provide a technical overview of the use of ultrasound in decompression research, particularly Doppler and brightness (B)-mode ultrasound. Further, we will discuss the strengths and limitations of these technologies and how new advancements are improving our ability to understand bubble behavior post-decompression.
人们普遍认为，气泡是减压病发展的必要但不充分条件。然而，由于直接在体内观察这一现象存在固有难度，关于环境压力降低（减压）后气泡的确切形成和行为仍存在悬而未决的问题。在减压研究中，通过超声采集来获取减压后这些气泡的信息。使用超声进行减压研究的结论受到不同研究小组所使用的方法和设备的可变性的强烈影响。这些差异对数据质量有重大影响，因此对结果的解释也有重大影响。本文的目的是提供超声在减压研究中的应用的技术概述，特别是多普勒和亮度（B）模式超声。此外，我们将讨论这些技术的优缺点，以及新技术的进步如何提高我们对减压后气泡行为的理解能力。
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