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第二代抗精神病药在儿科急诊医学中的应用。

Second-Generation Antipsychotic Use in Pediatric Emergency Medicine.

机构信息

From the Trainee, The Pediatric Research in Emergency Therapeutics (PRETx) Program, Division of Pediatric Emergency Medicine.

Clinical Professor, Division of Endocrinology, Department of Pediatrics.

出版信息

Pediatr Emerg Care. 2021 Mar 1;37(3):161-164. doi: 10.1097/PEC.0000000000002387.

Abstract

In recent years, the number of patients presenting to the emergency department with mental health complaints has been growing, alongside an increase in second-generation antipsychotic (SGAs) prescriptions for a variety of mental health conditions. Children treated with SGAs may have abnormalities, such as rapid weight gain and central adiposity, glucose intolerance, dyslipidemia, and hypertension; they may present to the pediatric emergency department with components of metabolic syndrome or type 2 diabetes, and a subsequent significant risk for cardiovascular complications later in life. Pediatric emergency department providers may serve as a safety net for patients to detect SGA-related metabolic complications, especially among vulnerable populations lacking access to primary care or psychiatric services.

摘要

近年来,因心理健康问题到急诊科就诊的患者数量不断增加,同时,各种精神疾病的第二代抗精神病药物(SGAs)处方也有所增加。接受 SGAs 治疗的儿童可能会出现异常,如体重迅速增加和中心性肥胖、葡萄糖耐量异常、血脂异常和高血压;他们可能会因代谢综合征或 2 型糖尿病的某些症状而到儿科急诊科就诊,并且随后在以后的生活中患心血管并发症的风险显著增加。儿科急诊科的医护人员可能会作为患者的安全网,以发现 SGA 相关的代谢并发症,特别是在那些缺乏初级保健或精神科服务的弱势群体中。

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