From the Trainee, The Pediatric Research in Emergency Therapeutics (PRETx) Program, Division of Pediatric Emergency Medicine.
Clinical Professor, Division of Endocrinology, Department of Pediatrics.
Pediatr Emerg Care. 2021 Mar 1;37(3):161-164. doi: 10.1097/PEC.0000000000002387.
In recent years, the number of patients presenting to the emergency department with mental health complaints has been growing, alongside an increase in second-generation antipsychotic (SGAs) prescriptions for a variety of mental health conditions. Children treated with SGAs may have abnormalities, such as rapid weight gain and central adiposity, glucose intolerance, dyslipidemia, and hypertension; they may present to the pediatric emergency department with components of metabolic syndrome or type 2 diabetes, and a subsequent significant risk for cardiovascular complications later in life. Pediatric emergency department providers may serve as a safety net for patients to detect SGA-related metabolic complications, especially among vulnerable populations lacking access to primary care or psychiatric services.
近年来,因心理健康问题到急诊科就诊的患者数量不断增加,同时,各种精神疾病的第二代抗精神病药物(SGAs)处方也有所增加。接受 SGAs 治疗的儿童可能会出现异常,如体重迅速增加和中心性肥胖、葡萄糖耐量异常、血脂异常和高血压;他们可能会因代谢综合征或 2 型糖尿病的某些症状而到儿科急诊科就诊,并且随后在以后的生活中患心血管并发症的风险显著增加。儿科急诊科的医护人员可能会作为患者的安全网,以发现 SGA 相关的代谢并发症,特别是在那些缺乏初级保健或精神科服务的弱势群体中。