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急性心肌梗死患者前往具备直接经皮冠状动脉介入治疗能力的中心时的院前延误及其原因

Pre-hospital Delay and Its Reasons in Patients With Acute Myocardial Infarction Presenting to a Primary Percutaneous Coronary Intervention-Capable Center.

作者信息

Mujtaba Syed F, Sohail Hina, Ram Jaghat, Waqas Muhammad, Hassan Muhammad, Sial Jawaid A, Naseeb Khalid, Saghir Tahir, Karim Musa

机构信息

Adult Cardiology, National Institute of Cardiovascular Diseases, Karachi, PAK.

Cardiology, National Institute of Cardiovascular Diseases, Larkana, PAK.

出版信息

Cureus. 2021 Jan 28;13(1):e12964. doi: 10.7759/cureus.12964.

Abstract

Objective This study aimed to assess the duration of pre-hospital delay among ST-Segment Elevation Myocardial Infarction (STEMI) patients and its contributing factors. Methodology A cross-sectional study was conducted at Rural Satellite Center in Larkana, Pakistan from May to September 2020. A total of 240 STEMI patients who underwent primary percutaneous coronary intervention (P-PCI) were included. The patients' demographic characteristics, index event characteristics, mode of transportation, misinterpretations, misdiagnoses, and financial problems were recorded. Data were analyzed using SPSS version 22.0 (IBM Corp., Armonk, NY, USA). Results The observed pre-hospital time was 120 minutes; 229 (median; interquartile range [IQR]). It was found that 33.3% of patients arrived within one hour of the symptom onset, while 20.4% of patients delayed hospital arrival for more than six hours. The delay rate was highest among patients aged 41 to 65 years. Moreover, delayed admissions were more common among females as compared to males (p=0.008). Among the causes of delay in hospital arrival were misinterpretation, misdiagnosis, and transportation and financial issues. Of these, misdiagnosis significantly influenced the delay rate, i.e., more than 50% of the misdiagnosed patients arrived hospital after six hours of symptom onset (p<0.05). Conclusion The P-PCI rural satellite center had a positive impact as the observed pre-hospital delay rate was considerably less as compared to that reported in the existing literature. Moreover, the confounding factors were misdiagnosis and misinterpretations. We need to develop the concept of immediate appropriate help-seeking among patients.

摘要

目的 本研究旨在评估ST段抬高型心肌梗死(STEMI)患者的院前延迟时间及其影响因素。方法 2020年5月至9月在巴基斯坦拉卡纳农村卫星中心开展了一项横断面研究。共纳入240例行直接经皮冠状动脉介入治疗(P-PCI)的STEMI患者。记录患者的人口统计学特征、索引事件特征、交通方式、误解、误诊及经济问题。使用SPSS 22.0版软件(美国纽约州阿蒙克市IBM公司)进行数据分析。结果 观察到的院前时间为120分钟(中位数;四分位间距[IQR]为229)。发现33.3%的患者在症状发作后1小时内到达,而20.4%的患者延迟入院超过6小时。41至65岁患者的延迟率最高。此外,女性延迟入院比男性更常见(p = 0.008)。入院延迟的原因包括误解、误诊以及交通和经济问题。其中,误诊对延迟率有显著影响,即超过50%的误诊患者在症状发作6小时后才入院(p<0.05)。结论 该农村卫星中心的P-PCI产生了积极影响,因为观察到的院前延迟率与现有文献报道相比显著更低。此外,混杂因素为误诊和误解。我们需要培养患者立即寻求适当帮助的意识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d9e/7912978/d731cd465ef2/cureus-0013-00000012964-i01.jpg

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