Unit of Otorhinolaryngology - Head and Neck Surgery, University of Brescia - ASST 'Spedali Civili di Brescia', Brescia, Italy.
Department of Otolaryngology - Head and Neck Surgery/Surgical Oncology, Princess Margaret Cancer Centre/University Health Network.
Curr Opin Otolaryngol Head Neck Surg. 2021 Apr 1;29(2):156-160. doi: 10.1097/MOO.0000000000000705.
The purpose of this review is to provide the reader with an overview of the present and future applications of bioengineering for head and neck reconstruction, ranging from the application of Computed Assisted Surgery (CAS) to the most recent advances in 3D printing and tissue engineering.
The use of CAS in head and neck reconstruction has been demonstrated to provide shorter surgical times, improved reconstructive accuracy of bone reconstruction, and achieves better alignment of bone segments in osteotomized reconstructions. Beyond its classical application in bone reconstructions, CAS has demonstrated reliability in the planning and harvesting of soft tissue flaps. To date, literature regarding bioengineering for head and neck reconstruction is mainly focused on in-vitro and animal model experiments; however, some pioneering reports on human patients suggest the potential feasibility of this technology.
Bioengineering is anticipated to play a key role in the future development of customized flaps for head and neck reconstruction. These technologies are particularly appealing as a new technology to address certain unsolved challenges in head and neck reconstruction.
本文旨在为读者概述生物工程在头颈部重建中的应用现状和未来发展方向,涵盖从计算机辅助手术(CAS)的应用到最新的 3D 打印和组织工程技术。
CAS 在头颈部重建中的应用已被证明可以缩短手术时间、提高骨重建的精确性,并实现截骨重建中骨段更好的对位。除了在骨重建中的经典应用外,CAS 在软组织皮瓣的规划和采集方面也表现出了可靠性。迄今为止,关于头颈部重建的生物工程文献主要集中在体外和动物模型实验上;然而,一些针对人类患者的开创性报告表明了这项技术的潜在可行性。
生物工程有望在未来头颈部重建的定制皮瓣发展中发挥关键作用。这些技术特别吸引人,因为它们是一种新技术,可以解决头颈部重建中某些尚未解决的挑战。