Gupta Anunay, Lokhandwala Yash, Rai Nitish, Malviya Amit
Department of Cardiology Vardhman Mahavir Medical College and Safdarjung Hospital Delhi India.
Department of Cardiology Lokmanya Tilak Municipal General Hospital Mumbai India.
J Arrhythm. 2020 Dec 18;37(1):103-112. doi: 10.1002/joa3.12453. eCollection 2021 Feb.
Adenosine has been used in the emergency treatment of arrhythmia for more than nine decades. However, cardiologists are often unfamiliar about its basic mechanism and various diagnostic and therapeutic uses, considering it mainly as a therapeutic drug for supraventricular tachycardia. This article discusses the role of adenosine relevant to emergency physicians, cardiologists, and electrophysiologists. Understanding of the mechanisms of adenosine and its electrophysiological effects is discussed first, followed by dosing, side effects, diagnostic, and therapeutic uses. Finally, the role of adenosine in the electrophysiology laboratory is discussed.
九十多年来,腺苷一直用于心律失常的紧急治疗。然而,心脏病专家通常对其基本机制以及各种诊断和治疗用途并不熟悉,主要将其视为室上性心动过速的治疗药物。本文讨论了腺苷对急诊医生、心脏病专家和电生理学家的作用。首先讨论对腺苷机制及其电生理效应的理解,接着是给药、副作用、诊断和治疗用途。最后,讨论腺苷在电生理实验室中的作用。