癌症研究中的患者来源异种移植模型
Patient-Derived Xenograft Models in Cancer Research.
作者信息
van Weerden Wytske M
机构信息
Department of Urology, Erasmus MC Cancer Institute, Room BE362, Erasmus University Medical Center, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands.
出版信息
Cancers (Basel). 2021 Feb 16;13(4):815. doi: 10.3390/cancers13040815.
Abstract
This series of 12 articles, consisting of 9 original articles and 3 reviews, is presented by international leaders in translational cancer research [...].
摘要
这一系列12篇文章，包括9篇原创文章和3篇综述，由转化癌症研究领域的国际领军人物撰写[……]
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Patient-Derived Xenograft Models in Cancer Research.癌症研究中的患者来源异种移植模型
Cancers (Basel). 2021 Feb 16;13(4):815. doi: 10.3390/cancers13040815.
2
Applications of patient-derived tumor xenograft models and tumor organoids.患者来源肿瘤异种移植模型和肿瘤类器官的应用。
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Establishment of an orthotopic patient-derived xenograft mouse model using uveal melanoma hepatic metastasis.使用葡萄膜黑色素瘤肝转移建立原位患者来源的异种移植小鼠模型。
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A novel patient-derived orthotopic xenograft model of esophageal adenocarcinoma provides a platform for translational discoveries.一种新型的食管腺癌患者来源的原位异种移植模型为转化研究提供了一个平台。
Dis Model Mech. 2019 Dec 17;12(12):dmm041004. doi: 10.1242/dmm.041004.
6
Generation of matched patient-derived xenograft in vitro-in vivo models using 3D macroporous hydrogels for the study of liver cancer.利用 3D 大孔水凝胶在体外-体内模型中生成匹配的患者来源异种移植物，用于肝癌研究。
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Generation and application of patient-derived xenograft models in pancreatic cancer research.患者来源异种移植模型在胰腺癌研究中的产生和应用。
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Characterization of drug responses of mini patient-derived xenografts in mice for predicting cancer patient clinical therapeutic response.在小鼠中对迷你患者来源异种移植物的药物反应进行特征分析，以预测癌症患者的临床治疗反应。
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Patient-derived xenograft models of non-small cell lung cancer for evaluating targeted drug sensitivity and resistance.非小细胞肺癌患者来源异种移植模型用于评估靶向药物敏感性和耐药性。
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10
Current status and perspectives of patient-derived xenograft models in cancer research.患者来源异种移植模型在癌症研究中的现状与展望
J Hematol Oncol. 2017 May 12;10(1):106. doi: 10.1186/s13045-017-0470-7.
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OncoVee™-MiniPDX-Guided Anticancer Treatment for Gastric Cancer Patients With Synchronous Liver Metastases: A Retrospective Cohort Analysis.OncoVee™-MiniPDX指导的同步肝转移胃癌患者的抗癌治疗：一项回顾性队列分析
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本文引用的文献
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Patient-Derived Xenograft and Organoid Models for Precision Medicine Targeting of the Tumour Microenvironment in Head and Neck Cancer.用于头颈部癌肿瘤微环境精准医学靶向治疗的患者来源异种移植和类器官模型
Cancers (Basel). 2020 Dec 12;12(12):3743. doi: 10.3390/cancers12123743.
2
Implementing Systems Modelling and Molecular Imaging to Predict the Efficacy of BCL-2 Inhibition in Colorectal Cancer Patient-Derived Xenograft Models.运用系统建模和分子成像技术预测BCL-2抑制在结直肠癌患者来源异种移植模型中的疗效。
Cancers (Basel). 2020 Oct 14;12(10):2978. doi: 10.3390/cancers12102978.
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Fast, In Vivo Model for Drug-Response Prediction in Patients with B-Cell Precursor Acute Lymphoblastic Leukemia.用于预测B细胞前体急性淋巴细胞白血病患者药物反应的快速体内模型
Cancers (Basel). 2020 Jul 13;12(7):1883. doi: 10.3390/cancers12071883.
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Applying Tissue Slice Culture in Cancer Research-Insights from Preclinical Proton Radiotherapy.组织切片培养在癌症研究中的应用——来自临床前质子放疗的见解
Cancers (Basel). 2020 Jun 16;12(6):1589. doi: 10.3390/cancers12061589.
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Cancers (Basel). 2020 May 25;12(5):1349. doi: 10.3390/cancers12051349.
6
Patient-Derived Xenograft Models of Pancreatic Cancer: Overview and Comparison with Other Types of Models.胰腺癌患者来源的异种移植模型：概述及与其他类型模型的比较
Cancers (Basel). 2020 May 22;12(5):1327. doi: 10.3390/cancers12051327.
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Multi-Modal PET and MR Imaging in the Hen's Egg Test-Chorioallantoic Membrane (HET-CAM) Model for Initial Testing of Target-Specific Radioligands.鸡胚绒毛尿囊膜（HET-CAM）模型中用于靶向特异性放射性配体初步测试的多模态PET和MR成像
Cancers (Basel). 2020 May 15;12(5):1248. doi: 10.3390/cancers12051248.
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