Belfeki N, Louarn N, Chouchane I, Abbadi A, Diamantis S
Department of Internal Medicine, Groupe Hospitalier Sud Ile de France, Melun.
Department of Nuclear Medicine, Clinique Saint Jean, Melun.
Reumatismo. 2021 Jan 18;72(4):252-254. doi: 10.4081/reumatismo.2020.1353.
Eosinophilic fasciitis is a rare connective tissue disease with a clinical presentation of scleroderma-like disease. We report a case of a 36-year-old female patient with a 6-month history of progressive stiffness involving her forearms and legs with joint pain. Laboratory examinations showed hypereosinophilia and elevated C-reactive protein. 18F FDG PET/CT showed diffuse and symmetrical increased uptake in the fasciae of the upper and lower limbs, sparing both muscles and fat tissues. Guided biopsy and histologic examination confirmed the diagnosis of eosinophilic fasciitis. 18F FDG PET/CT is of great help in the diagnosis of eosinophilic fasciitis, as it can guide the biopsy where FDG uptake is strongest and also help rule out possible associated neoplasms.
嗜酸性筋膜炎是一种罕见的结缔组织病，临床表现为硬皮病样疾病。我们报告一例36岁女性患者，有6个月进行性僵硬病史，累及前臂和腿部并伴有关节疼痛。实验室检查显示嗜酸性粒细胞增多和C反应蛋白升高。18F FDG PET/CT显示上肢和下肢筋膜弥漫性、对称性摄取增加，肌肉和脂肪组织未见受累。在其引导下进行活检及组织学检查确诊为嗜酸性筋膜炎。18F FDG PET/CT对嗜酸性筋膜炎的诊断有很大帮助，因为它可以在FDG摄取最强的部位引导活检，还有助于排除可能相关的肿瘤。
