Cherian Sujith V, Kaur Saranjit, Karanth Siddharth, Xian Jonathan Z, Estrada-Y-Martin Rosa M
Divisions of Critical Care, Pulmonary and Sleep Medicine, McGovern Medical School, University of Texas Health, Houston, TX, USA.
Ann Thorac Med. 2021 Jan-Mar;16(1):102-109. doi: 10.4103/atm.ATM_388_20. Epub 2021 Jan 14.
Electromagnetic navigational bronchoscopy (ENB) is an excellent tool to diagnose peripheral pulmonary nodules, especially in the setting of emphysema and pulmonary fibrosis. However, most of these procedures are done by interventional pulmonologists and academic tertiary centers under general anesthesia. Studies evaluating the diagnostic utility of this tool in safety-net community hospitals by pulmonologists not formally trained in this technology are lacking. The objective was to evaluate the diagnostic yield of ENB done in such a setting and its associated complications.
Retrospective chart review of consecutive ENB procedures over 5 years from 2014, since its inception in our institution-a safety-net community based hospital was performed. Multiple variables were analyzed to assess their impact on diagnostic yields.
After exclusion criteria were applied, 72 patients with 76 procedures were eventually included within our study, with an overall 1-year diagnostic yield of 80.2%. Sensitivity for malignancy was 73% and negative predictive value of 65%. Primary lung cancer was the most common diagnosis obtained, followed by tuberculosis (TB). The overall complication rates were low, with only 1 patient (1.3%) requiring hospitalization due to pneumothorax needing tube thoracostomy. No deaths or respiratory failures were noted within the cohort. The only significant variable affecting diagnostic yield was forced expiratory volume in 1 s. The presence of emphysema did not affect diagnostic yield.
ENB is safe and feasible with a high diagnostic success rate even when performed by pulmonologists not formally trained in interventional pulmonology in low resource settings under moderate sedation.
电磁导航支气管镜检查(ENB)是诊断周围型肺结节的一种优秀工具,尤其是在肺气肿和肺纤维化的情况下。然而,这些操作大多由介入肺科医生在学术三级中心在全身麻醉下进行。缺乏由未接受过该技术正规培训的肺科医生在安全网社区医院评估该工具诊断效用的研究。目的是评估在这种情况下进行的ENB的诊断率及其相关并发症。
对自2014年在我们机构(一家基于安全网社区的医院)开展ENB以来连续5年的ENB操作进行回顾性病历审查。分析多个变量以评估它们对诊断率的影响。
应用排除标准后,我们的研究最终纳入了72例患者的76次操作,总体1年诊断率为80.2%。恶性肿瘤的敏感性为73%,阴性预测值为65%。原发性肺癌是最常见的诊断结果,其次是肺结核(TB)。总体并发症发生率较低,只有1例患者(1.3%)因气胸需要胸腔闭式引流术而住院。该队列中未观察到死亡或呼吸衰竭。影响诊断率的唯一显著变量是第1秒用力呼气量。肺气肿的存在并不影响诊断率。
即使在资源有限的环境中,由未接受过介入肺科正规培训的肺科医生在中度镇静下进行ENB,也是安全可行的,诊断成功率高。