Mycetoma Research Centre, University of Khartoum, Khartoum, Sudan.
Institute for Endemic Diseases, University of Khartoum, Khartoum, Sudan.
Trans R Soc Trop Med Hyg. 2021 Apr 14;115(4):431-435. doi: 10.1093/trstmh/trab031.
Mycetoma is a chronic granulomatous disease that significant affects the subcutaneous tissue and deep structures. Mycetoma is caused by certain fungi (eumycetoma) or higher bacteria (actinomycetoma). The clinical presentation is variable and depends on the causative agent. For proper treatment and patient management, an accurate diagnosis of the species is mandatory. The disease mainly involves the extremities and it is rarely seen in the head and neck or other sites. In this communication, we present an interesting case of both invasive and aggressive mastoid bone eumycetoma caused by Madurella mycetomatis. Such cases are defied by complex challenges in finding effective surgical and medical treatments when the patient does not respond to both prolonged and different antifungal therapies.
足菌肿是一种慢性肉芽肿性疾病，会严重影响皮下组织和深部结构。足菌肿是由某些真菌（接合菌病）或更高等的细菌（放线菌病）引起的。临床表现多种多样，取决于病原体。为了进行适当的治疗和患者管理，必须对物种进行准确的诊断。该疾病主要累及四肢，很少见于头颈部或其他部位。在本通讯中，我们报告了一例由米黑根毛霉引起的侵袭性和侵袭性乳突骨接合菌病的有趣病例。当患者对长期和不同的抗真菌治疗均无反应时，此类病例在寻找有效手术和药物治疗方面存在复杂的挑战。
