Department of Dermatology, Ordu State Hospital, Ordu, Turkey.
J Cosmet Dermatol. 2021 Dec;20(12):4048-4051. doi: 10.1111/jocd.14048. Epub 2021 Mar 14.
Alopecia areata (AA) is an inflammatory condition that causes regional shedding without scarring on the hair or eyebrows, eyelashes, and beard. In studies conducted, it has been concluded that platelet/lymphocyte ratio (PLR), neutrophil/lymphocyte ratio (NLR), and mean platelet volume (MPV) are significant indicators of systemic inflammation in various diseases. In the present study, our aim was to examine these parameters in AA patients and to investigate their relationship with the disease.
A total of 135 AA patients and 135 healthy controls who did not have any systemic, inflammatory, infectious, or autoimmune diseases were included in this study. Demographic characteristics and complete blood count (CBC) results were analyzed retrospectively and recorded, and statistical analysis was performed.
PLR, NLR, and MPV values were not differ between AA patients and the control group.
It can be concluded that PLR, NLR, and MPV values are not convenient parameters to show inflammatory response in AA.
斑秃（AA）是一种炎症性疾病，会导致头发、眉毛、睫毛和胡须出现区域性脱落，且不会留下疤痕。在已进行的研究中，血小板/淋巴细胞比值（PLR）、中性粒细胞/淋巴细胞比值（NLR）和平均血小板体积（MPV）被认为是各种疾病中全身炎症的重要指标。本研究旨在检测 AA 患者的这些参数，并探讨其与疾病的关系。
本研究共纳入 135 例 AA 患者和 135 例无任何系统性、炎症性、感染性或自身免疫性疾病的健康对照者。回顾性分析并记录了这些患者的人口统计学特征和全血细胞计数（CBC）结果，并进行了统计学分析。
AA 患者和对照组的 PLR、NLR 和 MPV 值无差异。
PLR、NLR 和 MPV 值不是显示 AA 炎症反应的便捷参数。
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