Institute of Science in Healthy Ageing & HealthcarE (SHARE, University Medical Center Groningen (UMCG, University of Groningen, The Netherlands.
Department of Pharmacotherapy and Translational Research, University of Florida - College of Pharmacy, Gainesville, USA.
J Clin Pharm Ther. 2021 Oct;46(5):1238-1244. doi: 10.1111/jcpt.13402. Epub 2021 Mar 9.
Chemotherapy drugs are often administered in combinations with predefined interdependent doses and cycle intervals. As yet, there is no global standardization system to describe these complex regimens in a universally comprehensive manner. The aim of this review is to identify which efforts for standardization have been undertaken and which recommendations for databases and nomenclature of chemotherapy regimens are available.
A literature review was performed to identify all peer-reviewed full-text articles about oncology therapy regimen codification. In addition, the results of this search were evaluated and consensus recommendations from a European expert panel were subsequently added.
This review gives an overview of attempts to standardize chemotherapy nomenclature described in the literature, as well as of previously published identified gaps in regimen codification. In addition, we summarized the suggestions for improvement of chemotherapy codification found in the available literature, combining them with the expertise from a European expert panel of oncology pharmacists.
We believe that one of the most important error-prevention measures is standardization. However, there is a paucity of data how it may be achieved. Currently available data suggest that standardization has a positive impact on usability for data networks, prescription software, safety and the measurement of the quality of cancer care delivery. Standardization is also a strong pre-requisite for all discussions including oncology pharmacists and oncologists when evaluating chemotherapy regimen in countries in Europe but also all over the world. The recommendations compiled in this review can help to support overdue standardization efforts in this important therapeutic area.
化疗药物通常以预设的相互依赖的剂量和周期间隔组合使用。然而，目前还没有一种全球化的标准化系统可以全面描述这些复杂的方案。本综述的目的是确定已经进行了哪些标准化工作，以及有哪些关于化疗方案数据库和命名法的建议。
对有关肿瘤治疗方案编码的同行评审全文文章进行了文献回顾。此外，还评估了该搜索的结果，并随后添加了来自欧洲专家小组的共识建议。
本综述概述了文献中描述的标准化化疗命名法的尝试，以及方案编码中已确定的先前存在的差距。此外，我们还总结了文献中发现的改善化疗编码的建议，将其与来自欧洲肿瘤药学专家小组的专业知识相结合。
我们认为，最重要的错误预防措施之一是标准化。然而，关于如何实现标准化的数据很少。目前可用的数据表明，标准化对数据网络、处方软件、安全性以及衡量癌症护理提供的质量具有积极影响。标准化也是在评估欧洲和世界各地的化疗方案时，包括肿瘤药师和肿瘤学家在内的所有讨论的重要前提。本综述中汇编的建议可以帮助支持在这个重要治疗领域中进行的标准化工作。
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