Lieber Stefan, Evangelista-Zamora Rocio, Nunez Maximiliano, Tatagiba Marcos
Department of Neurological Surgery, Eberhard-Karls-University, University Hospital Tübingen, Tübingen, Germany.
Department of Neurological Surgery, Microsurgical Neuroanatomy Lab, University of Pittsburgh, Pittsburgh, Pennsylvania, United States.
J Neurol Surg B Skull Base. 2021 Feb;82(Suppl 1):S35-S36. doi: 10.1055/s-0039-3402056. Epub 2020 Mar 13.
We present a case of a sizeable foramen magnum meningioma that was resected through a C1 hemilaminectomy in prone (concorde) position. The patient is a 51-year-old woman with a 3-month history of progressive paresthesia of the upper and lower extremities, followed by gait disturbance, and hand apraxia. There was no complaint of nuchal pain. On magnetic resonance imaging (MRI) a briskly enhancing extra-axial, intradural craniospinal lesion, extending from the basion of the lower clivus, over the tectorial membrane to the middle of the axis' body was discovered. There was significant transposition and compression of the medulla and corresponding focal hyperintensity on T2-weighted imaging. On physical examination, the patient was ambulatory independently, notwithstanding a pronounced spinal ataxia. There were deficits in sensation and proprioception, as well as urinary retention, but preserved function of the lower cranial nerves. In view of the profound transposition of the medulla, utilization of the corridor created by the tumor seemed feasible and we felt that a limited C1 hemilaminectomy would provide sufficient microsurgical access thus obviating a more extensive and invasive approach to the craniocervical junction. A gross-total resection was achieved; histopathology confirmed a World Health Organization (WHO) grade I angiomatous meningioma with a low-proliferation index. The patient was discharged home 3 days after surgery and her spinal ataxia resolved completely within 3 months of out-patient rehabilitation. At 3-year follow-up, there was no indication of residual or recurrence. The link to the video can be found at: https://youtu.be/WyShbfr-xi0 .
我们报告一例大型枕骨大孔脑膜瘤病例,该肿瘤通过俯卧位(协和位)C1半椎板切除术切除。患者为一名51岁女性,有3个月渐进性上下肢感觉异常病史,随后出现步态障碍和手部失用症。无颈部疼痛主诉。磁共振成像(MRI)显示,一个轴外硬膜内快速强化的颅脊病变,从下斜坡基底延伸,越过小脑幕至枢椎椎体中部。延髓有明显移位和受压,T2加权成像上有相应的局灶性高信号。体格检查时,尽管患者有明显的脊髓性共济失调,但仍能独立行走。存在感觉和本体感觉缺陷以及尿潴留,但低位脑神经功能保留。鉴于延髓有明显移位,利用肿瘤形成的通道似乎可行,我们认为有限的C1半椎板切除术将提供足够的显微手术入路,从而避免对颅颈交界区采用更广泛、更具侵入性的方法。实现了肿瘤全切除;组织病理学证实为世界卫生组织(WHO)I级血管性脑膜瘤,增殖指数低。患者术后3天出院,门诊康复3个月内脊髓性共济失调完全消失。3年随访时,无残留或复发迹象。视频链接可在:https://youtu.be/WyShbfr-xi0 找到。