采用一种新的灵敏放射免疫分析法对不同年龄正常女性的降钙素水平进行评估。

Calcitonin levels in normal women of various ages evaluated with a new sensitive radioimmunoassay.

作者信息

Pedrazzoni M, Mantovani M, Ciotti G, Girasole G, Pioli G, Palummeri E

机构信息

Second Chair of Medical Clinics, University of Parma, Italy.

出版信息

Horm Metab Res. 1988 Feb;20(2):118-9. doi: 10.1055/s-2007-1010767.

DOI:10.1055/s-2007-1010767

PMID:3371863

Abstract

In order to establish the normal range of serum Calcitonin (CT), evaluated with a new, sensitive radioimmunoassay in normal women of various ages, 67 female subjects were examined. CT levels were detectable in all the subjects, with a reference interval (bounded by the 2.5 and 97.5 percentiles) of 3.6-16.9 pg/ml; a very slight decrease with age was observed (correlation coefficient = -0.24; P = 0.05; regression equation: CT = 9.55--0.042 x age). This assay seems sensitive enough to permit the measurement of CT in physiological conditions.

摘要

为了通过一种新的、灵敏的放射免疫分析法确定不同年龄正常女性血清降钙素（CT）的正常范围，对67名女性受试者进行了检查。所有受试者的CT水平均可检测到，参考区间（由第2.5和第97.5百分位数界定）为3.6 - 16.9 pg/ml；观察到随年龄有非常轻微的下降（相关系数 = -0.24；P = 0.05；回归方程：CT = 9.55 - 0.042×年龄）。该分析法似乎足够灵敏，能够在生理条件下测量CT。