Fuchs U
Prog Biochem Pharmacol. 1977;13:182-4.
The folds of the intimal surface do not represent the endothelia. Rather, they are produced by tissue shrinkage occurring during preparation, with the shrinking process proceeding in the arteriosclerotic bed differing from that in the normal vessel wall. Consequently, the surface appearance, or texture, of arteriosclerotic beds is different from that of the normal vessel wall. Administration of angiotensin results in the deposition of parietal microthrombi and fibrin filaments as well as in the adhesion of mononuclear leukocytes to the inner coat of the vessel.
内膜表面的褶皱并不代表内皮细胞。相反,它们是由制备过程中发生的组织收缩产生的,动脉硬化床中的收缩过程与正常血管壁中的不同。因此,动脉硬化床的表面外观或质地与正常血管壁不同。给予血管紧张素会导致壁层微血栓和纤维蛋白丝的沉积,以及单核白细胞粘附于血管内膜。