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免疫功能正常患者发生毛霉病:病例报告及文献复习。

Mucormycosis occurring in an immunocompetent patient: a case report and review of literature.

出版信息

Cesk Patol. 2020 Winter;56(4):223-226.

Abstract

Mucormycosis is an opportunistic fungal infection with a high fatality rate and is the third most common fungal infection that is invasive in nature, next to candidiasis and aspergillosis. The condition is generally vasotropic and angio-invasive in nature. It gets disseminated to a wider area locally and also exhibits a distant spread. It is usually associated with medically compromised patients. However, mucormycosis in immunocompetent individuals is gaining attention as several cases have been reported throughout the world with a high incidence of such cases being reported from the Indian subcontinent. It is attributed to the poor socio-economic status and triggered by the local trauma due to unhygienic setup or poor health care. The pathway of pathogenesis is not clearly understood in immunocompetent patients and therefore becomes a matter of great concern. Here, we report one such case of mucormycosis affecting the maxillary region following tooth extraction in a 42-year-old male.

摘要

毛霉病是一种机会性真菌感染,死亡率很高,是继念珠菌病和曲霉菌病之后第三种常见的侵袭性真菌感染。该病通常具有血管趋向性和血管侵袭性。它会在局部扩散到更广泛的区域,并表现出远处播散。它通常与身体状况不佳的患者有关。然而,免疫功能正常者中的毛霉病越来越受到关注,因为世界各地都有报道,而且在印度次大陆报告的此类病例发生率很高。这归因于较差的社会经济地位,并因不卫生的环境或较差的医疗保健导致的局部创伤而引发。在免疫功能正常的患者中,发病机制的途径尚不清楚,因此成为一个非常关注的问题。在这里,我们报告了一例 42 岁男性在拔牙后上颌区域发生毛霉病的病例。

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