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脑卒中后三个月自我报告抑郁感的预测因素:一项纵向队列研究。

Predictors for self-reported feeling of depression three months after stroke: A longitudinal cohort study.

机构信息

Department of Clinical Neuroscience, Rehabilitation Medicine, Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden.

出版信息

J Rehabil Med. 2021 Mar 25;53(3):jrm00170. doi: 10.2340/16501977-2816.

Abstract

OBJECTIVE

Depression and impaired cognition are common consequences of stroke. The aim of this study was to determine whether cognitive impairment 36-48 h post-stroke could predict self-reported feeling of depression 3 months post-stroke.

DESIGN

A longitudinal, cohort study.

PATIENTS

Patients aged ≥ 18 years at stroke onset.

METHODS

Cognition was screened using the Montreal Cognitive Assessment, 36-48 h after admission to the stroke unit at Sahlgrenska University Hospital. Information about self-reported feeling of depression 3 months post-stroke was retrieved from Riksstroke (the national quality register for stroke in Sweden). Bootstrapped binary logistic regression analyses were performed.

RESULTS

Of 305 patients, 42% were female, median age was 70 years, and 65% had mild stroke. Three months post-stroke, 56% of patients had self-reported feeling of depression; of these, 65% were female. Impaired cognition at baseline could not predict self-reported feeling of depression 3 months later. The odds for self-reported feeling of depression were twice as high in female patients (odds ratio 2.01; 95% confidence interval, 0.20-1.22; p < 0.01).

CONCLUSION

Impaired cognition early after stroke could not predict self-reported feeling of depression 3 months post-stroke. Compared with male patients, female patients had twice the odds of self-reported feeling of depression.

摘要

目的

抑郁和认知障碍是中风的常见后果。本研究旨在确定中风后 36-48 小时的认知障碍是否可以预测中风后 3 个月的自我报告抑郁感。

设计

纵向队列研究。

患者

中风发病时年龄≥18 岁的患者。

方法

在哥德堡萨尔格伦斯卡大学医院中风病房入院后 36-48 小时,使用蒙特利尔认知评估对认知进行筛查。中风后 3 个月自我报告抑郁感的信息从 Riksstroke(瑞典全国中风质量登记处)中检索。进行了 bootstrap 二分类逻辑回归分析。

结果

在 305 名患者中,42%为女性,中位年龄为 70 岁,65%为轻度中风。中风后 3 个月,56%的患者有自我报告的抑郁感;其中 65%为女性。基线时的认知障碍不能预测 3 个月后的自我报告抑郁感。女性患者自我报告抑郁感的几率是男性患者的两倍(比值比 2.01;95%置信区间,0.20-1.22;p<0.01)。

结论

中风后早期的认知障碍不能预测中风后 3 个月的自我报告抑郁感。与男性患者相比,女性患者自我报告抑郁感的几率是男性的两倍。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b17/8814838/4cf1d399314d/JRM-53-3-2774-g001.jpg

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