Turner J, Parsons O A
Oklahoma Center for Alcohol and Drug-Related Research, University of Oklahoma Health Sciences Center, Oklahoma City 73190.
J Stud Alcohol. 1988 May;49(3):281-7. doi: 10.15288/jsa.1988.49.281.
Women alcoholics (N = 54) had significantly worse performance on clusters of verbal and nonverbal abstracting - problem-solving tasks than peer nonalcoholic controls (N = 48). On the nonverbal cluster, alcoholic women with an alcoholic parent or sibling (FH+) performed significantly poorer than peer alcoholics without such a family history (FH-) and nonalcoholic FH+ and FH- groups. On the verbal cluster, FH+ alcoholics performed significantly worse than the nonalcoholic groups. FH- alcoholics did not differ significantly from the nonalcoholic groups on either of the clusters. There were no differences between FH+ and FH- nonalcoholics on the two types of tasks. The results suggest that female alcoholics have a generalized deficit on cognitive tasks involving abstracting and problem-solving, and that these deficits tend to be more pronounced in alcoholic women with a positive family history of alcohol abuse. Whether these deficits are due to a premorbid lowering of abstracting - problem-solving abilities in the FH+ individuals who subsequently become alcoholics, or are the result of a selective vulnerability of these cognitive processes to the effects of alcohol abuse in such subjects, or some combination of these factors, remains to be investigated.
女性酗酒者(N = 54)在言语和非言语抽象及解决问题任务组上的表现明显比同龄非酗酒对照组(N = 48)差。在非言语任务组中,有酗酒父母或兄弟姐妹的酗酒女性(FH+)比没有这种家族史的同龄酗酒者(FH-)以及非酗酒的FH+和FH-组表现明显更差。在言语任务组中,FH+酗酒者的表现明显比非酗酒组差。FH-酗酒者在任何一个任务组中与非酗酒组都没有显著差异。FH+和FH-非酗酒者在这两种任务类型上没有差异。结果表明,女性酗酒者在涉及抽象和解决问题的认知任务上存在普遍缺陷,而且这些缺陷在有酗酒家族史阳性的酗酒女性中往往更为明显。这些缺陷是由于随后成为酗酒者的FH+个体病前抽象和解决问题能力降低,还是由于这些认知过程在此类受试者中对酒精滥用影响的选择性易感性,或者是这些因素的某种组合,仍有待研究。