内啡肽/κ 阿片受体系统的基础：从分布到信号转导和功能。
Fundamentals of the Dynorphins/Kappa Opioid Receptor System: From Distribution to Signaling and Function.
机构信息
Department of Psychiatry and Biobehavioral Sciences, Shirley and Stefan Hatos Center for Neuropharmacology, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Unit on Neuromodulation and Synaptic Integration, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA.
出版信息
Handb Exp Pharmacol. 2022;271:3-21. doi: 10.1007/164_2021_433.
Abstract
This chapter provides a general introduction to the dynorphins (DYNs)/kappa opioid receptor (KOR) system, including DYN peptides, neuroanatomy of the DYNs/KOR system, cellular signaling, and in vivo behavioral effects of KOR activation and inhibition. It is intended to serve as a primer for the book and to provide a basic background for the chapters in the book.
摘要
本章对强啡肽（DYN）/κ 阿片受体（KOR）系统进行了概述，内容包括 DYN 肽、DYN/KOR 系统的神经解剖学、细胞信号转导以及 KOR 激活和抑制的体内行为效应。其目的是为本书提供一个入门，并为本书各章提供一个基础知识背景。
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