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感染奥斯特他线虫且呈现三种不同“综合征”的牛血浆中的牛胃蛋白酶原形式

Forms of bovine pepsinogen in plasma from cattle with three different 'syndromes' of Ostertagia ostertagi infection.

作者信息

McKellar Q A, Eckersall P D, Duncan J L, Armour J

机构信息

Department of Veterinary Pharmacology, University of Glasgow Veterinary School, Bearsden.

出版信息

Res Vet Sci. 1988 Jan;44(1):29-32.

PMID:3375583
Abstract

Calves infected orally with third stage larvae of Ostertagia ostertagi or infected with adult O ostertagi by direct transplantation into the abomasum had raised plasma pepsinogen activity, as did four-year-old dairy cattle challenged with O ostertagi third stage larvae on five occasions. Using fast protein liquid chromatography two forms of pepsinogen; pepsinogen 1 (PG1) and pepsinogen 2 (PG2) were identified in each of the parasitic infection regimes.

摘要

经口感染奥斯特他线虫第三期幼虫的犊牛,或通过直接移植到皱胃感染成年奥斯特他线虫的犊牛,其血浆胃蛋白酶原活性升高,五岁奶牛经五次感染奥斯特他线虫第三期幼虫后也是如此。使用快速蛋白质液相色谱法,在每种寄生虫感染情况下均鉴定出两种形式的胃蛋白酶原:胃蛋白酶原1(PG1)和胃蛋白酶原2(PG2)。

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