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衰弱对鼻衄入院的影响:一项回顾性队列研究。

The impact of frailty on epistaxis admission, a retrospective cohort study.

机构信息

Department of Otolaryngology, University Hospital Crosshouse, Kilmarnock, UK.

出版信息

Clin Otolaryngol. 2021 Sep;46(5):983-990. doi: 10.1111/coa.13765. Epub 2021 Mar 29.

Abstract

OBJECTIVES

Epistaxis is frequently managed with intra-nasal packing devices, traditionally requiring patient admission. Current COVID-19 guidelines encourage ambulatory care where possible in this patient cohort. This paper aims to establish the impact of the Clinical Frailty Scale, anticoagulant/antiplatelet therapeutics and season variation on pre-pandemic admissions to help identify patients suitable for ambulatory epistaxis management.

DESIGN

Retrospective cohort study SETTING: Scottish Regional Health Board PARTICIPANTS: Adult patients attending secondary care with epistaxis between March 2019 and March 2020.

MAIN OUTCOME MEASURES

Likelihood of epistaxis hospital admission based on Clinical Frailty Scale.

RESULTS

299 epistaxis presentations were identified, of which 122 (40.8%) required admission. Clinical Frailty Scale of ≥4 had an increased likelihood of admission (OR 3.15 (95% CI:1.94-5.16), P < .05). In the majority of presentations (66.2%), patients were taking either an antiplatelet or anticoagulant. Of these presentations, the use of an anticoagulant (OR: 2.00 (95% CI: 1.20-3.33), P < .05 and dual antiplatelet (OR: 2.82 (95% CI: 1.02-7.86), P < .05) demonstrated increased likelihood of admission.

CONCLUSIONS

We have shown that frailty increases the risk of admission in adult patients presenting with epistaxis. Clinical Frailty Scale (CFS) could be utilised in risk stratification to identify suitable patients for outpatient management. Patients with CFS ≤ 3 could be considered for outpatient management of their epistaxis. It is likely that patients with CFS ≥4 on anticoagulant or dual antiplatelet will require admission.

摘要

目的

鼻出血常采用鼻腔内填塞装置进行治疗,传统上需要住院。目前,COVID-19 指南鼓励在可能的情况下对这一患者群体进行门诊治疗。本文旨在通过临床虚弱量表、抗凝/抗血小板治疗和季节变化来确定该人群的入院前情况,以帮助识别适合门诊管理的鼻出血患者。

设计

回顾性队列研究

地点

苏格兰地区卫生委员会

参与者

2019 年 3 月至 2020 年 3 月期间在二级保健机构就诊的鼻出血成年患者。

主要观察指标

基于临床虚弱量表评估鼻出血患者住院的可能性。

结果

共发现 299 例鼻出血发作,其中 122 例(40.8%)需要住院治疗。临床虚弱量表评分≥4 与住院的可能性增加相关(OR 3.15(95% CI:1.94-5.16),P<0.05)。在大多数发作(66.2%)中,患者正在服用抗血小板或抗凝药物。在这些发作中,使用抗凝药物(OR:2.00(95% CI:1.20-3.33),P<0.05)和双联抗血小板药物(OR:2.82(95% CI:1.02-7.86),P<0.05)与住院的可能性增加相关。

结论

我们已经表明,虚弱程度增加了成年鼻出血患者入院的风险。临床虚弱量表(CFS)可用于风险分层,以识别适合门诊管理的合适患者。CFS 评分≤3 的患者可考虑门诊管理其鼻出血。CFS≥4 的抗凝或双联抗血小板患者可能需要住院治疗。

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