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髋臼微骨折技术在关节镜治疗股骨髋臼撞击综合征软骨损伤中的益处:一项多中心前瞻性随机研究的两年结果

[Benefits of the Acetabular Microfracture Technique in Arthroscopic Treatment of Chondral Defects in Femoroacetabular Impingement Syndrome: Two-Year Results of a Multicenter Prospective Randomized Study].

作者信息

Rafi M, Kautzner J, Havel O, Kalina R, Vyskočil V, Zeman P

机构信息

Ortopedické oddělení, Kroměřížská nemocnice, a.s., Kroměříž.

Klinika dětské a dospělé ortopedie a traumatologie 2. Lékařské fakulty Univerzity Karlovy a Fakultní nemocnice v Motole, Praha.

出版信息

Acta Chir Orthop Traumatol Cech. 2021;88(1):18-27.

PMID:33764863
Abstract

PURPOSE OF THE STUDY Two-year clinical results of a multicenter prospective randomized study in patients with arthroscopically treated Femoro - acetabular Impingement syndrome and concurrently performed microfracture for grade IV chondral lesions of the acetabulum. MATERIAL AND METHODS The study evaluated a group of 55 patients of the originally enrolled 92 patients with the underlying diagnosis of FAI syndrome with intraoperatively confirmed grade IV acetabular chondropathy of up to 4 cm2 in size, who had undergone a comprehensive hip arthroscopy (correction of structural cam-type and/or pincer-type deformity, labral refixation or partial labral resection etc.) performed by two experienced surgeons. The patients were randomized intraoperatively using a closed envelope method into two groups. In Group 1 (31 patients), microfractures for chondral defects was performed, while in Group 2 the patients underwent a defect debridement procedure only. The studied group included a total of 7 professional and 48 recreational athletes (33 men and 22 women), with the mean age of 34.4 in Group 1 and 31.1 in Group 2. Preoperatively and 6, 12 and 24 months postoperatively the modified Harris Hip Score (mHHS) parameters and VAS score were evaluated and also revision surgeries, conversion to endoprosthesis, and occurrence of complications were recorded. RESULTS Preoperatively, no statistical difference between the two groups was found in the studied parameters (mHHS and VAS). Postoperatively (after 6, 12 and 24 months), in both groups a statistically significant increase in mHHS and VAS score was reported. When comparing the mHHS parameter at individual evaluated times in Group 1 and Group 2, a statistically significant difference was confirmed at 12 and 24 months after surgery (P < 0.001), namely in favour of Group 1. At 6 months postoperatively, no statistically significant difference in this parameter between the two groups was confirmed (P = 0.068). When comparing the VAS score parameter in these two groups at individual times, no statistically significant difference was confirmed at 6 and 12 months after surgery (P= 0.83 / P= 0.39). A statistically significant difference in the VAS score parameter was observed only at 24 months after surgery, namely in favour of Group 1 (P< 0.037). In the course of the follow-up period, altogether 3 patients (2 patients from Group 1) were indicated for revision hip arthroscopy and in 1 female patient an endoprosthesis was implanted. No severe intraoperative or postoperative complications were observed. DISCUSSION In agreement with other authors worldwide, the arthroscopic treatment of FAI syndrome, if indicated and performed correctly, was confirmed to improve the clinical condition of patients postoperatively, regardless of the technique used in treating the chondral defect. Based on our results as well as conclusions of other world authors, in treating the grade IV defects of smaller size it is appropriate, in treating the cartilage, to prefer the microfracture surgery, which is less demanding both technically and financially and contrary to mere debridement allows to fill the original defect by fibrocartilage tissue. CONCLUSIONS The benefits of the acetabular microfracture in patients with the FAI syndrome treated arthroscopically were confirmed. A statistically significant difference between the two studied groups was reported in the mHHS parameter at 12 and 24 months after surgery and also in the VAS parameter at 24 months in favour of the group with performed microfracture. In both the studied groups, the arthroscopy resulted in a statistically significant improvement of the assessed quality of life parameters. Key words: hip arthroscopy, femoroacetabular impingement syndrome, chondral defect, microfracture, abrasive chondroplasty.

摘要

研究目的

一项多中心前瞻性随机研究的两年临床结果,该研究针对接受关节镜治疗的股骨髋臼撞击综合征患者,同时对髋臼IV级软骨损伤进行微骨折治疗。

材料与方法

该研究评估了最初纳入的92例患者中的55例,这些患者的基本诊断为FAI综合征,术中证实髋臼软骨病IV级,面积达4平方厘米,由两位经验丰富的外科医生进行了全面的髋关节镜检查(矫正结构型凸轮型和/或钳夹型畸形、盂唇重新固定或部分盂唇切除等)。患者在术中采用封闭信封法随机分为两组。第1组(31例患者)对软骨缺损进行微骨折治疗,而第2组患者仅接受缺损清创手术。研究组共有7名职业运动员和48名业余运动员(33名男性和22名女性),第1组的平均年龄为34.4岁,第2组为31.1岁。术前以及术后6、12和24个月评估改良Harris髋关节评分(mHHS)参数和视觉模拟评分(VAS),并记录翻修手术、转换为假体植入以及并发症的发生情况。

结果

术前,两组在研究参数(mHHS和VAS)方面未发现统计学差异。术后(6、12和24个月后),两组的mHHS和VAS评分均有统计学意义的显著提高。比较第1组和第2组在各个评估时间的mHHS参数,术后12个月和24个月确认存在统计学显著差异(P < 0.001),即第1组更优。术后6个月,两组在该参数上未确认存在统计学显著差异(P = 0.068)。比较两组在各个时间的VAS评分参数,术后6个月和12个月未确认存在统计学显著差异(P = 0.83 / P = 0.39)。仅在术后24个月观察到VAS评分参数存在统计学显著差异,即第1组更优(P < 0.037)。在随访期间,共有3例患者(第1组2例)接受了髋关节镜翻修手术,1例女性患者植入了假体。未观察到严重的术中或术后并发症。

讨论

与全球其他作者一致,FAI综合征的关节镜治疗,如果指征明确且操作正确,无论治疗软骨缺损所采用的技术如何,术后均可改善患者的临床状况。基于我们的结果以及其他世界作者的结论,对于较小尺寸的IV级缺损,在治疗软骨时,微骨折手术更为合适,该手术在技术和经济方面要求较低,与单纯清创不同,它可以通过纤维软骨组织填充原始缺损。

结论

证实了髋臼微骨折对接受关节镜治疗的FAI综合征患者的益处。术后12个月和24个月,两组在mHHS参数上存在统计学显著差异,术后24个月在VAS参数上也存在统计学显著差异,微骨折组更优。在两个研究组中,关节镜检查均使评估的生活质量参数有统计学意义的显著改善。

关键词

髋关节镜检查;股骨髋臼撞击综合征;软骨缺损;微骨折;磨削软骨成形术

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